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Lack of mutagenicity of products formed by ammoniation of gossypol

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Journal of the American Oil Chemists’ Society

Abstract

Gossypol distributed on an inert gel carrier was treated in a pressurized ammoniation chamber used to detoxify aflatoxin-contaminated cottonseed meal. Ames tests for mutagenicity were performed on untreated gossypol and on fractions eluted sequentially from the gel. Nonammoniated gossypol was not mutagenic nor were any of the products formed from gossypol by ammoniation.

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References

  1. Wong, J.J., and D.P.H. Hsieh., Proc. Natl. Acad. Sci. USA 73:2241 (1976).

    Article  PubMed  CAS  ADS  Google Scholar 

  2. Austwick, P.K.C., in “Mycotoxic Fungi, Mycotoxins, Mycotoxicoses. An Encyclopedic Handbook,” edited by T.D. Wylie and L.G. Morehouse, Marcel Dekker, Inc., New York and Basel, 1978, pp. 279–301.

    Google Scholar 

  3. Norred, W.P., and R.E. Morrissey, Toxicol. and Appl. Pharmacology 70:96 (1983).

    Article  CAS  Google Scholar 

  4. Lawlor, T.E., S.R. Haworth, E. Zeigler, D.L. Park and L.S. Lee, JAOCS (in press).

  5. Park, D.L., L.S. Lee and S.P. Koltun, JAOCS 61:1071 (1984).

    CAS  Google Scholar 

  6. Haworth, S.R., T.E. Lawlor, E. Zeiger, L.S. Lee and D.L. Park, JAOCS (in press).

  7. Berardi, L.C., and L.A. Goldblatt, in “Toxic Constituents of Plant Foodstuffs,” 2nd ed., edited by I.E. Liener, Academic Press, N.Y., 1980, pp. 183–237.

    Google Scholar 

  8. Mozgov, I.E., Veterinariya, No. 8–9 (1946).

  9. Lee, L.S., S.P. Koltun and J.B. Stanley, JAOCS 61:1607 (1984).

    Article  CAS  Google Scholar 

  10. de Peyster, A., The New England Journal of Medicine, p. 275 (1979).

  11. Majumdar, S.K., J.D. Thatcher, E.H. Dennis, A. Cutrone, M. Stockage and M. Hammond, J. Herid. 73:76 (1983).

    Google Scholar 

  12. McCann, J., N.E. Spingarn, J. Kobori and B.N. Ames, Proc. Natl. Acad. Sci. USA 72:979 (1975).

    Article  PubMed  CAS  ADS  Google Scholar 

  13. Ames, B.N., J. McCann and E. Yamasaki, Mutat. Res. 31:347 (1975).

    PubMed  CAS  Google Scholar 

  14. Dunn, J.J., L.S. Lee and A. Ciegler, Environ. Mutagen. 4:19 (1982).

    Article  PubMed  CAS  Google Scholar 

  15. Reid, R.L., Feedstuffs, Nov. 6, p. 41 (1972).

Download references

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Lee, L.S., Ehrlich, K.C., Daigle, K.W. et al. Lack of mutagenicity of products formed by ammoniation of gossypol. J Am Oil Chem Soc 62, 1573–1574 (1985). https://doi.org/10.1007/BF02541688

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  • DOI: https://doi.org/10.1007/BF02541688

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