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Monoenoic fatty acids in human brain lipids: Isomer identification and distribution

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Lipids

Abstract

The carbon chain length distribution and the double bond positional isomer composition of the monoenoic fatty acids of the lipids of total human brain tissue have been determined using gas chromatography and gas chromatography/mass spectrometry of the fatty acid methyl and picolinyl esters. The even chain length monoenoic C16 to C28 fatty acids contain predominantly two positional isomer series, the n−7 and n−9cis homologues, whose relative proportion varies significantly with chain length. The odd chain length long-chain fatty acids consist of n−8 and n−10 isomers, whereas the odd chain length very long-chain (more than 22 carbon) fatty acids are n−7 and n−9 isomers.

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Abbreviations

amu:

Atomic mass units

GC:

gas-chromatography

GC/MS:

gas chromatography/mass spectrometry

TLC:

thin-layer chromatography

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Authors and Affiliations

  1. the Department of Chemical Pathology, Adelaide Medical Centre for Women and Children, 72 King William Road, 5006, North Adelaide, South Australia, Australia

    D. W. Johnson, K. Beckman, A. J. Fellenberg, B. S. Robinson & A. Poulos

Authors
  1. D. W. Johnson
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  2. K. Beckman
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  3. A. J. Fellenberg
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  4. B. S. Robinson
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  5. A. Poulos
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Johnson, D.W., Beckman, K., Fellenberg, A.J. et al. Monoenoic fatty acids in human brain lipids: Isomer identification and distribution. Lipids 27, 177–180 (1992). https://doi.org/10.1007/BF02536174

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  • DOI: https://doi.org/10.1007/BF02536174

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