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The influence of purines on plasma lecithin: Cholesterol acyltransferase activity in the rat

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Lipids

Abstract

The activity of plasma lecithin: cholesterol acyltransferase (LCAT) in the rat is significantly inhibited in vitro by guanine, xanthine, and hypoxanthine. LCAT activity decreases with increase in xanthine concentration. The other two purines, adenine and uric acid, had no significant effect.

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Authors and Affiliations

  1. Laboratoire de Biochimie, Faculté de Médecine de Rangueil, chemin du Vallon, 31054, Toulouse Cedex, France

    M. L. Solera

  2. Institut National de la Santé et de la Recherche Médicale, C.H.R. de Purpan, 31052, Toulouse Cedex, France

    N. Dousset

  3. Laboratoire de Biochimie, Faculté de Médecine de Rangueil, chemin du Vallon, 31054, Toulouse Cedex, France

    P. Valdiguie

  4. Institut National de la Santé et de la Recherche Médicale, C.H.R. de Purpan, 31052, Toulouse Cedex, France

    L. Douste-Blazy

Authors
  1. M. L. Solera
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  2. N. Dousset
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  3. P. Valdiguie
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  4. L. Douste-Blazy
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Solera, M.L., Dousset, N., Valdiguie, P. et al. The influence of purines on plasma lecithin: Cholesterol acyltransferase activity in the rat. Lipids 13, 619–621 (1978). https://doi.org/10.1007/BF02535826

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  • DOI: https://doi.org/10.1007/BF02535826

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