Skip to main content
SpringerLink
Log in

Sterols and their biosynthesis in some freshwater bivalves

  • Published:
Lipids

Abstract

A number of free sterols and sterol esters of three freshwater mussels was separated and identified. A slow rate of biosynthesisde novo of sterols was demonstrated inAnodonta cygnea. Injected cholesterol was found to undergo esterification, oxidation, Δ22-dehydrogenation and C-24 alkylation. Methyl-[14C]methionine was proved to be incorporated in C-24 alkylsterols. Abnormally large amounts of cholesterol injected inA. cygnea were metabolized toward restoration of the normal composition of sterols. This was achieved by intensified metabolism of cholesterol, mainly by conjugation, oxidation and Δ22-dehydrogenation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Yasuda, S. (1971) Yukagaku 20, 479–483.

    CAS  Google Scholar 

  2. Voogt, P. (1975) Comp. Biochem. Physiol. B50, 505–510.

    Google Scholar 

  3. Idler, D.R. and Wiseman, P. (1971) Int. J. Biochem. 2, 91.

    Article  CAS  Google Scholar 

  4. Pennock, J. (1977) in Biochemistry of Lipids II, International Review of Biochemistry, (Goodwin, T., ed.) Vol. 14, pp. 153, Univ. Park Press, Baltimore, MD.

    Google Scholar 

  5. Fagerlund, U., and Idler, D. (1960) Can. J. Biochem. Physiol. 38, 997–1002.

    PubMed  CAS  Google Scholar 

  6. Fagerlund, U. and Idler, D. (1961) Can. J. Biochem. Physiol. 39, 505–509.

    PubMed  CAS  Google Scholar 

  7. Salaque, A., Barbier, M. and Lederer, E. (1966) Comp. Biochem. Physiol. 19, 45–51.

    Article  CAS  Google Scholar 

  8. Walton, M.J. and Pennock, J.F. (1972) Biochem. J. 127, 471–479.

    PubMed  CAS  Google Scholar 

  9. Fagerlund, U. and Idler, D. (1961) Can. J. Biochem. Physiol. 39, 1347–1355.

    PubMed  CAS  Google Scholar 

  10. Teshima, S. and Kanazawa, A. (1973) Nippon Suisan Gakkaishi 39, 1309–1314.

    CAS  Google Scholar 

  11. de Rosa, M., Minale, L. and Sodano, G. (1973) Comp. Biochem. Physiol. B45, 883.

    Google Scholar 

  12. Minale, L., and Sodano, G. (1977) in Marine Natural Products Chemistry (Faulkner, D.J., and Fenical, W.H., eds.), pp. 87–109, Plenum, New York.

    Google Scholar 

  13. Milkova, Ts., Popov, S., Stoilov, I., Marekov, N., Andreev, St., Wulfson, N. and Zaikin, V. (1978) 11th Int. Symp. Chem. Nat. Prod. 2, 128–131.

    CAS  Google Scholar 

  14. Chobanov, D., Tarandjiiska, R. and Chobanova, R. (1976) J. Am. Oil Chem. Soc. 53, 48–51.

    PubMed  CAS  Google Scholar 

  15. Smith, A., Rubinstein, J. and Goad, L. (1973) Biochem. J. 135, 443–455.

    PubMed  CAS  Google Scholar 

  16. Kobayashi, M. and Mitsuhashi, H. (1975) Steroids 26, 605.

    Article  PubMed  CAS  Google Scholar 

  17. Elsevier's Encyclopedia of Organic Chemistry (1954) 14S, 1771.

  18. Rubinstein, I. and Goad, L. (1974) Phytochemistry 13, 485–487.

    Article  CAS  Google Scholar 

  19. Khalil, M., Idler, D. and Patterson, G. (1980) Lipids 15, 69–73.

    Article  CAS  Google Scholar 

  20. Milkova, Ts., Popov, S., Marekov, N., Dilov, H. and Yordanova, S. (1977) Comp. Rend. Acad. Bulg. Sci. 30, 1027–1029.

    CAS  Google Scholar 

  21. Milkova, Ts., Popov, S., Marekov, N. and Andreev, St. (1980) Comp. Biochem. Physiol. B67, 633–638.

    Google Scholar 

  22. Milkova, Ts., Popov, S., Marekov, N., Stoilov, I., Andreev, St. and Kovachev, J. (1980) Bull. Soc. Chim. Belg. 89, 1081–1085.

    Article  CAS  Google Scholar 

  23. Apsimon, J. and Burnel, D. (1980) Comp. Biochem. Physiol. 65B, 567–571.

    CAS  Google Scholar 

  24. Ballantine, J.A., Roberts, J.C. and Morris, R.J. (1980) Comp. Biochem. Physiol. 67B, 75.

    CAS  Google Scholar 

  25. Pierce, A., Pierce, H., Unrau, A., Oehlschlager, A., Subden, R. and Renaud, R. (1979) Can. J. Biochem. 57, 112–116.

    Article  PubMed  CAS  Google Scholar 

  26. Swift, M., White, D. and Gkassemieh, M. (1980) Lipids 15, 129–132.

    Article  CAS  Google Scholar 

  27. Teshima, S., Kanazawa, A. and Miyawaki, H. (1979) Comp. Biochem. Physiol. B63, 323–328.

    Google Scholar 

  28. Goad, L.J. (1978) in Marine Natural Products (Scheuer, P.J., ed.) Vol. 2, pp. 83–104, Academic Press, New York.

    Google Scholar 

  29. Goad, L.J. (1978) in Marine Natural Products (Scheuer, P.J., ed.) Vol. 2, pp. 98–100, Academic Press, New York.

    Google Scholar 

  30. Yasuda, S. (1973) Comp. Biochem. Physiol. B44, 41.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Organic Chemistry and Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria

    S. Popov, I. Stoilov & N. Marekov

  2. Research Institute of Mineral Resources, 1113, Sofia, Bulgaria

    G. Kovachev

  3. Museum of Natural History, 1000, Sofia, Bulgaria

    St. Andreev

Authors
  1. S. Popov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. Stoilov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. Marekov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Kovachev
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. St. Andreev
    View author publications

    You can also search for this author in PubMed Google Scholar

About this article

Cite this article

Popov, S., Stoilov, I., Marekov, N. et al. Sterols and their biosynthesis in some freshwater bivalves. Lipids 16, 663–669 (1981). https://doi.org/10.1007/BF02535061

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02535061

Keywords

Search

Navigation