Skip to main content
Log in

The thiobarbituric acid test for lipid peroxidation: Structure of the adduct with malondialdehyde

  • Methods
  • Published:


The complete structure of the red crystalline 2∶1 adduct from thiobarbituric acid and malondialdehyde has been unambiguously determined by FTIR and high-field1H and13C NMR studies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others


  1. (1980) Autoxidation in Food and Biological Systems (Simic, M.G., and Karel, M., eds.) Plenum Press, New York.

    Google Scholar 

  2. Gray, J.I. (1978) J. Am. Oil Chem. Soc. 55, 539–546.

    CAS  Google Scholar 

  3. Sinnhuber, R.O.; Yu, T.C., and Yu, Te Chang (1958) Food Res. 23, 626–633.

    CAS  Google Scholar 

  4. Porter, N.A.; Nixon, J., and Issac, R. (1976) Biochim. Biophys. Acta 441, 506–512.

    PubMed  CAS  Google Scholar 

  5. Pryor, W.A. (1980) in Molecular Basis of Environmental Toxicity (Bhatnagar, R.S., ed.) pp. 15–20, Ann Arbor Science, Ann Arbor.

    Google Scholar 

  6. Baumgartner, W.A.; Baker, N.; Hill, V.A., and Wright, E.T. (1975) Lipids 10, 309–311.

    Article  PubMed  CAS  Google Scholar 

  7. Marcuse, R., and Johansson, L. (1973) J. Am. Oil Chem. Soc. 50, 387–391.

    PubMed  CAS  Google Scholar 

  8. Willis, E.D. (1964) Biochim. Biophys. Acta 84, 475–477.

    Google Scholar 

  9. Nair, V.; Vietti, D.E., and Cooper, C.S. (1981) J. Am. Chem. Soc. 103, 3030–3036.

    Article  CAS  Google Scholar 

  10. Levy, G.C.; Lichter, R.L., and Nelson, G.L. (1980) Carbon-13 Nuclear Magnetic Resonance Spectroscopy, Wiley-Interscience, New York.

    Google Scholar 

  11. Rosenthal, S.N., and Fendler, J.H. (1976) in Advances in Physical Organic Chemistry (Gold, V. and Bethel, D., eds.) pp. 279–424, Academic Press, New York.

    Google Scholar 

  12. Johnson, L.F., and Jankowski, W.C. (1972) Carbon-13 NMR Spectra, Wiley, New York.

    Google Scholar 

Download references

Author information

Authors and Affiliations


About this article

Cite this article

Nair, V., Turner, G.A. The thiobarbituric acid test for lipid peroxidation: Structure of the adduct with malondialdehyde. Lipids 19, 804–805 (1984).

Download citation

  • Received:

  • Issue Date:

  • DOI: