Abstract
Instrumental neutron activation analysis was used for the determination of several trace elements in blood and tissue samples. Results are reported for calcium and iron, for which remarkable changes of the concentrations in the affected tissues were found. The levels and the changes with time of these concentrations can be explained with a participation of the two elements in the following processes: Calcium: 1. Fibrin formation in fracture haematoma blood (FHB) and in the crust of punch-hole wounds in the skin (rats). 2. Haemolysis in FHB-deposits (rabbits). Iron: Formation of collagen in fascia and muscle incision wounds (rabbits). The iron enrichments in the area of complication-free wound are not predominantly caused by a wound haematoma.
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F. LUX, R. ZEISLER, Z. Anal. Chem., 261 (1972) 314.
J. SCHUSTER, F. LUX, R. ZEISLER, Mschr. Unfallheilkunde, 76 (1973) 537.
F. LUX, R. ZEISLER, J. Radioanal. Chem., 19 (1974) 289.
F. LUX, R. ZEISLER, J. SCHUSTER, Langenbecks Arch. Chir., 337 (1974) 615.
F. LUX, R. ZEISLER, J. SCHUSTER, Trans. Am. Nuclear Soc., 21 Supplement 3 (1975) 1.
F. LUX, J. SCHUSTER, R. ZEISLER, J. Radioanal. Chem., 32 (1976) 229.
Trace Elements in Human Health and Disease, Vol. 1, A. S. PRASAD, D. OBERLEAS (Eds), Academic Press, New York, 1976.
M. CHVAPIL, J. HURYCH, E. EHRLICHOVA, Exp. Med. Surg., 26 (1968) 52.
J. W. BAINS, D. T. CRAWFORD, A. S. KETCHEM, Ann. Surg., 164 (1966) 243.
G. KENT, F. I. VOLINI, O. T. MINICK, E. ORFEI, J. HUERGA, Am. J. Pathol., 45 (1964) 129.
D. J. PROCKOP, K. JUVA, Proc. Natl. Acad. Sci. U.S.A., 53 (1965) 661.
B. PETERKOFSKY, S. UNDENFRIEND, J. Biol. Chem., 238 (1963) 3966.
R. M. DONATI, E. A. LEVRI, L. R. STROMBERG, Proc. Soc. Exp. Biol. Med., 139 (1972) 367.
E. L. LICHTI, J. A. SCHILLING, H. M. SHURLEY, Am. J. Surg., 123 (1972) 253.
E. L. LICHTI, M. TURNER, J. H. HENZEL, “Changes in serum zinc levels following periods of increased metabolic activity and differences in arterial and venous plasma zinc concentrations following surgically inflicted wounds”, Trace Substances in Environmental Health, IV, D. HEMPHILL (Ed), University of Missouri Press, Columbia, Mo., 1971.
G. BLÜMEL, Acta Chir. Austr., 4 (1970) 122.
Noch unveröffentlicht. Vgl. auch D. BOŽANIĆ, Dissertation, Technische Universität München, 1977.
F. LUX, D. BOŽANIĆ, G. BLÜMEL, W. ERHARDT, Mikrochim. Acta, 1978 I (1978) 35.
L. SACHS, Angewandte Statistik, Springer Verlag, Berlin, 1974, S. 386.
R. C. CAMPBELL, Statistische Methoden für Biologie und Medizin, Georg Thieme Verlag, Stuttgart, 1971, S. 68.
F. L. SIEGEL, Structure and Bonding, Vol. 17, Springer Verlag, Berlin, 1973, S. 243.
S. M. RAPOPORT, Medizinische Biochemie, VEB Verlag Volk und Gesundheit, Berlin, 1973, S. 822.
H. J. HERNANDEZ-RICHTER, H. STRUCK, Die Wundheilung, Georg Thieme Verlag, Stuttgart, 1970.
G. HEGEMANN, “Wundheilung und Wundbehandlung”, Lehrbuch der Chirurgie, H. HELLNER, R. NISSEN, K. VOSSSCHULTE (Hrsg), Georg Thieme Verlag, Stuttgart, 1970, S. 4.
S. M. RAPOPORT, Medizinische Biochemie, VEB Berlag Volk und Gesundheit, Berlin, 1973, S. 686.
S. M. RAPOPORT, Medizinische Biochemie, VEB Verlag Volk und Gesundheit, Berlin, 1973, S. 690.
B. R. OLSEN, R. A. BERG, K. I. KIVIRIKKO, D. J. PROCKOP, Eur. J. Biochem., 35 (1973) 135.
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Lux, F., Božanić, D., Blümel, G. et al. Aktivierungsanalytische Untersuchung des Verhaltens Biologischer Spurenelemente in der Wundheilung. J. Radioanal. Chem. 58, 289–303 (1980). https://doi.org/10.1007/BF02533800
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DOI: https://doi.org/10.1007/BF02533800