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Sterol-polyene antibiotic complexation: Probe of membrane structure

  • Symposium: Function of Steroids and Other Isopentenoid
  • Published:
Lipids

An Erratum to this article was published on 01 December 1978

Abstract

Polyene antibiotics are useful tools for studying the role of sterols in biological membranes. The interaction of polyene antibiotics with membrane-bound sterols in artificial membrane systems, prokaryotic and eukaryotic cells, and lipid-containing viruses is reviewed. The pentaene macrolide, filipin, is shown to serve as a probe of phosphatidylcholine-sterol interaction and of the localization of cholesterol in the membrane of mycoplasmas.

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Authors and Affiliations

  1. Department of Chemistry, Queens College of the City University of New York, 11367, Flushing, New York

    Robert Bittman

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  1. Robert Bittman
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Additional information

An erratum to this article is available at http://dx.doi.org/10.1007/BF02533834.

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Bittman, R. Sterol-polyene antibiotic complexation: Probe of membrane structure. Lipids 13, 686–691 (1978). https://doi.org/10.1007/BF02533746

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  • DOI: https://doi.org/10.1007/BF02533746

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