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Cholesteryl ester and triacylglycerol fatty acids in type V hyperlipidemia

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Lipids

Abstract

The fatty acid compositions of plasma cholesteryl esters (CE) and triacylglycerols (TG) from seven healthy individuals and five patients with type V hyperlipoproteinemia were determined. Very low density (VLDL), low density (LDL) and high density lipoproteins (HDL) were isolated. The lipids were extracted from the lipoproteins and the triacylglycerols and cholesteryl esters separated for analysis. The fatty acid compositions of triacylglycerols from healthy and type V individuals were very similar. The cholesteryl esters from type V patients had increased contents of palmitic and decreased amounts of linoleic and arachidonic acids as compared to the normal individuals. The fatty acid composition of the cholesteryl esters from the high density lipoproteins had the greatest deviation. The fatty acid compositions of the triacylglycerols from the two groups were similar. However, the triacylglycerols in all lipoprotein fractions contained more palmitic and oleic and less linoleic and arachidonic acids than the cholesteryl esters.

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References

  1. Frederickson, D.S., J.L. Goldstein, and M.S. Brown, in “The Metabolic Basis of Inherited Disease,” 4th Ed, Edited by J.B. Stanbury, J.B. Wyngaarden, and D.S. Frederickson, McGraw Hill, New York, 1978, pp. 643–646.

    Google Scholar 

  2. Carlson, L.A., A.G. Olsson, and D. Ballantyne, Atherosclerosis 26:603 (1974).

    Article  Google Scholar 

  3. Brown, W., M.L. Baginsky, and C. Enholm, in “Hyperlipidemia,” Edited by B.M. Rifkind and R.I. Levy, Grune & Stratton, New York, 1977, pp. 103–112.

    Google Scholar 

  4. Manual of Laboratory Operations, Lipid Research Clinics Program, Lipid and Lipoprotein Analysis, DHEW Publ. No. (NIH) 76-628 (1974).

  5. Gordon, D.T., R.E. Pitas, and R.G. Jensen, Lipids 10:858 (1975).

    Article  Google Scholar 

  6. Newton, R.S., R.E. Pitas, and R.G. Jensen, Lipids 10:858 (1975).

    Article  PubMed  CAS  Google Scholar 

  7. Folch, J., M. Lees, and G.H. Sloane-Stanley, J. Biol. Chem. 226:497 (1957).

    PubMed  CAS  Google Scholar 

  8. Kramer, C.Y., J. Dairy Sci. 61:848 (1978).

    Article  Google Scholar 

  9. Kudchodkar, B.J., and H.S. Sohdi, Clin. Chim. Acta 68:187 (1976).

    Article  PubMed  CAS  Google Scholar 

  10. Allard, C., J. Davignon, Y.L. Marcel, C. Goulet, K. Kuda, M. Alteresco, Y. Caradec, and D. Plante, Can. J. Biochem. 51:1509 (1973).

    Article  PubMed  CAS  Google Scholar 

  11. Bang, H.D., E.H. Theysen, and J. Thygesen, Acta Med. Scand. 184:241 (1968).

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Nutritional Sciences, University of Connecticut, 06268, Storrs, Connecticut

    R. G. Jensen, R. M. Clark, S. A. Gerrior & M. B. Fey

  2. Baylor College of Medicine, The Methodist Hospital, 77025, Houston, Texas

    A. M. Gotto Jr.

Authors
  1. R. G. Jensen
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  2. R. M. Clark
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  3. S. A. Gerrior
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  4. M. B. Fey
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  5. A. M. Gotto Jr.
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Jensen, R.G., Clark, R.M., Gerrior, S.A. et al. Cholesteryl ester and triacylglycerol fatty acids in type V hyperlipidemia. Lipids 14, 691–694 (1979). https://doi.org/10.1007/BF02533457

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  • DOI: https://doi.org/10.1007/BF02533457

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