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Effect of polyunsaturated fatty acids of the α-linolenic series on the development of rat testicles

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Lipids

Abstract

The effect of 22∶6ω3 acid provided by dietary fish oil on the development of germinal tissue of rat testes, fatty acid composition of lipids, and linoleic or α-linolenic acid Δ6 desaturation capacity was investigated. Results were compared to those obtained in animals fed methyl palmitate and sunflower seed oil (linoleate). At 7 and 9 weeks of age, development of germinal tissue of animals fed fish oil was normal. The fatty acid composition showed a decrease in 22∶5ω6 acid content and an increase in 22∶6ω3 acid in triacylglycerol, phosphatidylcholine, and phosphatidylethanolamine. The fatty acid Δ6 desaturation capacity of testicules microsomes was increased. It is suggested that 22∶6ω3 acid may functionally replace 22∶5ω6 acid in germinal tissue.

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References

  1. Bieri, J.G., and E.L. Prival, Comp. Biochem. Physiol. 15:275 (1965).

    Article  PubMed  CAS  Google Scholar 

  2. Holman, R., and H.H. Hofstetter, JAOCS 42:540 (1965).

    PubMed  CAS  Google Scholar 

  3. Davis, J.T., and J.G. Coniglio, J. Reprod. Fert. 14:407 (1967).

    Article  CAS  Google Scholar 

  4. Albert, A., in “Sex and Internal Secretions,” Edited by W.C. Young, Williams and Wilkins, Baltimore, 1961, pp. 305–365.

    Google Scholar 

  5. Knorr, D.W., T. Vanka-Perttula, and M.B. Lipsett, Endocrinology 86:1298 (1970).

    Article  PubMed  CAS  Google Scholar 

  6. Davis, J.T., R.B. Bridges, and J.G. Coniglio, Biochem. J. 98:342 (1966).

    PubMed  CAS  Google Scholar 

  7. Brenner, R.R., and P. Jose, J. Nutr. 85:196 (1965).

    PubMed  CAS  Google Scholar 

  8. Peluffo, R.O., S. Ayala, and R.R. Brenner, Am. J. Physiol. 218:669 (1970).

    PubMed  CAS  Google Scholar 

  9. Ayala, S., G. Gaspar, R.R. Brenner, R.O. Peluffo, and W. Kunau, J. Lipid Res. 14:296 (1973).

    PubMed  CAS  Google Scholar 

  10. Folch, J., M. Lees, and G.M. Sloane-Stanley, J. Biol. Chem. 226:497 (1957).

    PubMed  CAS  Google Scholar 

  11. Gaspar, O., S. Ayala, R.R. Brenner, and M.A. Restelli, Acta Physiol. Lat. Am. 25:41 (1975).

    Google Scholar 

  12. Stoffel, W., F. Chu, and E.M. Ahrens, J.R. Anal. Chem. 31:307 (1959).

    Article  CAS  Google Scholar 

  13. Ackman, R.G., R.D. Burgher, and P.M. Jangaard, Can. J. Biochem. Physiol. 41:1627 (1963).

    PubMed  CAS  Google Scholar 

  14. Ackman, R.G., and R.D. Burgher, J. Chromatogr. 11:185 (1963).

    Article  PubMed  CAS  Google Scholar 

  15. Ackman, R.G., JAOCS 40:564 (1963).

    Google Scholar 

  16. Leblond, C.P., and J. Clermont, Ann. N.Y. Acad. Sci. 55:548 (1952).

    PubMed  CAS  Google Scholar 

  17. Klenk, E., and K. Oette, Z. Physiol. Chem. 318:86 (1960).

    CAS  Google Scholar 

  18. Sprecher, H., Fed. Proc. 31:1451 (1972).

    PubMed  CAS  Google Scholar 

  19. Davis, J.T., and J.G. Coniglio, J. Biol. Chem. 241:610 (1966).

    PubMed  CAS  Google Scholar 

  20. Bridges, R.B., and J.G. Coniglio, Lipids 5:628 (1970).

    Article  PubMed  CAS  Google Scholar 

  21. Coniglio, J.G., R.B. Bridges, and J. Ghosal, Riv. Ital. Sostanza Grasse 51:312 (1974).

    CAS  Google Scholar 

  22. Carpenter, M., Biochim. Biophys. Acta 231:52 (1971).

    PubMed  CAS  Google Scholar 

  23. Castuma, J.C. A. Catalá, and R.R. Brenner, J. Lipid Res. 13:783 (1972).

    PubMed  CAS  Google Scholar 

  24. Peluffo, R.O., A.M. Nervi, and R.R. Brenner, Biochim Biophys. Acta 441:25 (1976).

    PubMed  CAS  Google Scholar 

  25. Brenner, R.R., in “Function and Biosnythesis of Lipids,” “Advances in Experimental Medicine and Biology Series,” Vol. 83, Edited by R.G. Bazán, R.R. Brenner, and N.M. Giusto, Plenum Press, New York, 1977, pp. 85–101.

    Google Scholar 

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Author notes

  1. Rodolfo R. Brenner (Member) & César Gómez Dumm (Member)

    Present address: Carrera del Investigador Científico of the Consejo Nacional de Investigaciones Científicas y Técnicas, Argentina

Authors and Affiliations

  1. Cátedra de Bioquímica, Instituto de Fisiología and Instituto de Histología, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina

    Sixta Ayala, Rodolfo R. Brenner (Member) & César Gómez Dumm (Member)

Authors
  1. Sixta Ayala
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  2. Rodolfo R. Brenner
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  3. César Gómez Dumm
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Ayala, S., Brenner, R.R. & Dumm, C.G. Effect of polyunsaturated fatty acids of the α-linolenic series on the development of rat testicles. Lipids 12, 1017–1024 (1977). https://doi.org/10.1007/BF02533328

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  • DOI: https://doi.org/10.1007/BF02533328

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