Abstract
Detailed investigation was made of the triacylglycerol structure of native, simulated, and interesterified peanut oils, which had previously been shown to differ markedly in their atherogenic potential. By means of chromatographic and stereospecific analyses, it was shown that the more atherogenic native oil contains a significantly greater proportion of triacylglycerols with linoleic insn-2-position and arachidic, behenic, and lignoceric acids insn-3-position than the synthetic oils. It is suggested that the atherogenicity may arise from a relative metabolic unavailability of the linoleic acid from the native oil, which may be due in part to the presence of long chain saturated acids in the outer position. This might render the oil metabolically more saturated than the interesterified oils of the same total fatty acid composition, which contain a much greater proportion of the linoleic acid in the primary positions of the triacylglycerol molecule. The identification of specific triacylglycerols may allow the experimental testing of this hypothesis by feeding synthetic triacylglycerols incorporating the potentially atherogenic features.
Similar content being viewed by others
References
Kritchevsky, D., S.A. Tepper, D. Vesselinovitch, and R.W. Wissler, Atherosclerosis 14:53 (1971).
Kritchevsky, D., S.A. Tepper, D. Vesselinovitch, and R.W. Wissler, Ibid. 17:225 (1973).
Kritchevsky, D., Am. J. Clin. Nutr. 23:1105 (1970).
Kritchevsky, D., S.A. Tepper, H.K. Kim, J.A. Story, D. Vesselinovitch, and R.W. Wissler, Exp. Mol. Pathol. 24:375 (1976).
Morley, N., and A. Kuksis, J. Biol. Chem. 247:6389 (1972).
Paltauf, F., F. Esfandi, and A. Holasek, FEBS Lett. 40:119 (1974).
Mattson, F.H., J.H. Benedict, J.B. Martin, and L.W. Beck, J. Nutr. 48:335 (1952).
Yurkowski, M., and H. Brockerhoff, Biochim. Biophys. Acta 125:55 (1966).
Thomas, A.E., III, J.E. Scharoun, and H. Ralston, JAOCS 42:789 (1965).
Breckenridge, W.C., and A. Kuksis, J. Lipid Res. 9:388 (1968).
Brockerhoff, H., Ibid. 6:10 (1965).
Brockerhoff, H., Lipids 6:942 (1971).
Wessels, H., and N.S. Rajagopal, Fette Seifen Anstrichm. 71:543 (1969).
Kuksis, A., L. Marai, and J.J. Myher, JAOCS 50:193 (1973).
Myher, J.J., and A. Kuksis, J. Chromatogr. Sci. 13:138 (1975).
Kuksis, A., and L. Marai, Lipids 2:217 (1967).
Author information
Authors and Affiliations
About this article
Cite this article
Myher, J.J., Marai, L., Kuksis, A. et al. Acylglycerol structure of peanut oils of different atherogenic potential. Lipids 12, 775–785 (1977). https://doi.org/10.1007/BF02533264
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02533264