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On the site of the microbiological reduction of cholesterol to coprostanol in the rat

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Lipids

Abstract

The microbiological reduction of the 5-ene bond of cholesterol (cholest-5-en-3β-ol) to form coprostanol (5β-cholestan-3β-ol) occurs in the gastrointestinal tract of many species. Data are presented which show that this activity occurs predominantly in the ceca in cholesterol fed rats. This explains the report by others that the removal of the ceca causes coprostanol to disappear from the feces.

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References

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Authors and Affiliations

  1. Department of Biochemistry Mississippi Agricultural and Forestry Experiment Station, Mississippi State University, P.O. Drawer BB, 39762, Mississippi State, Mississippi

    Thomas F. Kellogg

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  1. Thomas F. Kellogg
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Kellogg, T.F. On the site of the microbiological reduction of cholesterol to coprostanol in the rat. Lipids 8, 658–659 (1973). https://doi.org/10.1007/BF02533155

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  • DOI: https://doi.org/10.1007/BF02533155

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