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Metabolism of 2,4-3H-14α-methyl-5α-ergost-8-enol and 2,4-3H-5α-ergosta-8,14-dienol inOchromonas malhamensis

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Lipids

Abstract

Tritium-labeled 14α-methyl-5α-ergost-8-enol and 5α-ergosta-8,14-dienol were converted to brassicasterol and poriferasterol inOchromonas malhamensis. This indicates that the organism can rearrange these sterol structures so that they contain the naturally occurring 5(6) double bond, and suggests thatO. malhamensis is able to introduce a 24(28) double bond into a nine-carbon saturated side chain which is alkylated to produce a C-29 sterol.

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Authors and Affiliations

  1. Department of Botany, University of Maryland, 20742, College Park, Maryland

    John H. Adler & G. W. Patterson

Authors
  1. John H. Adler
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  2. G. W. Patterson
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Additional information

Scientific article no. A2202, contribution no. 5180, of the Maryland Agricultural Experiment Station.

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Adler, J.H., Patterson, G.W. Metabolism of 2,4-3H-14α-methyl-5α-ergost-8-enol and 2,4-3H-5α-ergosta-8,14-dienol inOchromonas malhamensis . Lipids 11, 634–636 (1976). https://doi.org/10.1007/BF02532878

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  • DOI: https://doi.org/10.1007/BF02532878

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