Advertisement

Lipids

, Volume 9, Issue 2, pp 117–120 | Cite as

Effects of anabolic and progestational agents upon triglycerides and triglyceride kinetics in normals and hyperlipemic patients

  • Ronald Fallat
  • Charles J. Glueck
Symposium: Effect of Drugs on Lipid Metabolism Presented at the AOCS Spring Meeting, New Orleans

Abstract

Progestational and anabolic-androgenic compounds may have extensive effects upon plasma triglycerides, triglyceride clearing enzymes, and upon mechanisms of triglyceride clearing from the plasma. This article centers upon recent advances in the understanding of the mode of action of these compounds, both in normals and in patients with hypertriglyceridemia.

Keywords

Lipase Triglyceride Oral Contraceptive Plasma Triglyceride Normal Woman 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Brody, S., J. Kerstell, L. Nilsson, and A. Svanborg, Acta Med. Scand. 183:3 (1968).Google Scholar
  2. 2.
    Gershberg, H., M.A. Hulse, and Z. Javier, Obstet. Gynecol. 31:186 (1968).PubMedCrossRefGoogle Scholar
  3. 3.
    Sachs, B.A., L. Wolfman, and N. Herzig, Obstet. Gynecol. 34:530 (1969).PubMedGoogle Scholar
  4. 4.
    Hazzard, W.R., M.J. Spiger, J.D. Bagdade, and E.L. Bierman, New Eng. J. Med. 280:471 (1969).PubMedCrossRefGoogle Scholar
  5. 5.
    Corredor, D.G., L.V. Mendelson, G. Sabeh, J.H. Sunder, and T.S. Danowski, Clin. Pharmacol. Ther. 11:188 (1970).PubMedGoogle Scholar
  6. 6.
    Kekki, M., and E.A. Nikkila, Metabolism 20:878 (1971).PubMedCrossRefGoogle Scholar
  7. 7.
    Pyorala, K., T. Pyorala, V. Lampinem, and M.R. Taskinen, Acta Obstet. Gynecol. Scand (Suppl.) 9:28 (1971).Google Scholar
  8. 8.
    Rossner, S., U. Larsson-Cohn, L.A. Carlson, and J. Boberg, Acta Med. Scand. 190:301 (1971).PubMedCrossRefGoogle Scholar
  9. 9.
    Schenker, J.G., A. Pinson, and Z. Polishuk, Fert. Steril. 22:604 (1971).Google Scholar
  10. 10.
    Stokes, T., and V. Wynn, Lancet 2:677 (1971).PubMedCrossRefGoogle Scholar
  11. 11.
    Wynn, V., Clin. Sci. 40:17 (1971).Google Scholar
  12. 12.
    Gershberg, H., J. Reprod. Med. 5:15 (1970).Google Scholar
  13. 13.
    Oliver, M.F., Brit. Med. J. 2:210 (1970).PubMedGoogle Scholar
  14. 14.
    Bickerstaff, E.R., and J. MacDonald Holmes, Ibid. 1:726 (1967).PubMedCrossRefGoogle Scholar
  15. 15.
    Vessey, M.P., and R. Doll, Ibid. 2:651 (1969).PubMedGoogle Scholar
  16. 16.
    Slack, J., Lancet 2:1380 (1969).PubMedCrossRefGoogle Scholar
  17. 17.
    Spellacy, W.N., K.L. Carlson, and S.A. Birk, Diabetes 16:590 (1967).PubMedGoogle Scholar
  18. 18.
    Spellacy, W.N., K.L. Carlson, and S.L. Schade, J. Amer. Med. Ass. 202:451 (1967).CrossRefGoogle Scholar
  19. 19.
    Spellacy, W.N., K.L. Carlson, S.A. Birk, and S.L. Schade, Metabolism 17:496 (1968).PubMedCrossRefGoogle Scholar
  20. 20.
    Spellacy, W.N., R.P. Bendel, W.C. Buhi, and S.A. Birk, Fert. Steril. 20:892 (1969).Google Scholar
  21. 21.
    Spellacy, W.M., W.C. Buhi, C.H. Spellacy, L.E. Moses, and J.W. Goldzieher, Amer. J. Obstet. Gynecol. 106:173 (1970).Google Scholar
  22. 22.
    Wynn, V., and J.W.H. Doar, Lancet 2:761 (1969).PubMedCrossRefGoogle Scholar
  23. 23.
    Ham, J.M., and R. Rose, Amer. J. Obstet. Gynecol. 105:628 (1969).Google Scholar
  24. 24.
    Larsson-Cohn, U., Acta Endocrinol. (Suppl). 155:173 (1971).Google Scholar
  25. 25.
    Larsson-Cohn W., L.A. Carlson, and J. Boberg, Acta. Med. Scand. 190:301 (1971).PubMedGoogle Scholar
  26. 26.
    Fabian, E., A. Stork, J. Koblkova, and J. Sponarova, Cas. Lek. Cesk. 43:1277 (1970).Google Scholar
  27. 27.
    Beck, P., H.A. Salhanick, D.M. Kipnis, and R.L. Vande Wiele, “Metabolic Effects of Gonadal Hormones and Contraceptive Steroids,” Plenum Press, New York, N.Y., 1969, p. 97.Google Scholar
  28. 28.
    Beck, P., J. Clin. Endocr. 30:785 (1970).PubMedCrossRefGoogle Scholar
  29. 29.
    Glueck, C.J., S. Ford, P. Steiner, S. Buxton, and R. Fallat, Amer. J. Obstet. Gynecol. 116:689 (1973).Google Scholar
  30. 30.
    Nikkila, E.A., and M. Kekki, Acta Med. Scand. 190:49 (1971).PubMedCrossRefGoogle Scholar
  31. 31.
    Frank, A., “Proceedings of the 1968 Deuel Conference on Lipids,” U.S. Department of Health, Education, and Welfare Washington, D.C. 1969, p. 95.Google Scholar
  32. 32.
    Sohdi, H.S., B.J. Kudchodkar, and L. Horlick, Metabolism 20:309 (1971).CrossRefGoogle Scholar
  33. 33.
    Reaven, G.M., D.B. Hill, R.C. Gross, and J.W. Farquhar, J. Clin. Invest. 44:1826 (1965).PubMedCrossRefGoogle Scholar
  34. 34.
    Havel, R.J., J.P. Kane, E.O. Balasse, N. Segel, and L.V. Basso, Ibid. 49:2017 (1970).PubMedGoogle Scholar
  35. 35.
    Glueck, C.J., S. Ford, P. Steiner, and R. Fallat, Metabolism, 22:807 (1973).PubMedCrossRefGoogle Scholar
  36. 36.
    Glueck, C.J., F. Swanson, and J. Fishback, Metabolism 20:691 (1971).PubMedCrossRefGoogle Scholar
  37. 37.
    LaRosa, J.C., R.I. Levy, H.G. Windmueller, and D.S. Fredrickson, J. Lipid Res. 13:356 (1972).PubMedGoogle Scholar

Copyright information

© American Oil Chemists’ Society 1974

Authors and Affiliations

  • Ronald Fallat
    • 1
  • Charles J. Glueck
    • 2
  1. 1.Lipoprotein Research LaboratoryCincinnati General HospitalCincinnati
  2. 2.General Clinical Research CenterCincinnati General HospitalCincinnati

Personalised recommendations