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Isolation of a trimer of α-tocopherol from mammalian liver

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Lipids

Abstract

Evidence is presented for the formation in mammalian liver of a trimeric metabolite of α-tocopherol. This compound has been shown to be identical to a trimer produced by oxidation of α-tocopherol with alkaline K3Fe(CN)6. In addition, confirmation was obtained for the occurrence in vivo of a dimeric metabolite reported previously. These compounds, together with tocopheryl-p-quinone, are postulated to arise from reactions with lipid-free radicals or peroxides in the course of the antioxidant action of vitamin E.

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Authors and Affiliations

  1. Division of Nutritional Biochemistry, Department of Animal Science, University of Illinois, Urbana, Illinois

    H. H. Draper, A. S. Csallany & Mei Chiu

Authors
  1. H. H. Draper
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  2. A. S. Csallany
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  3. Mei Chiu
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Draper, H.H., Csallany, A.S. & Chiu, M. Isolation of a trimer of α-tocopherol from mammalian liver. Lipids 2, 47–54 (1967). https://doi.org/10.1007/BF02532000

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  • DOI: https://doi.org/10.1007/BF02532000

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