Lipids

, Volume 8, Issue 9, pp 534–535 | Cite as

Volume-dependent transfer of free fatty acids from ehrlich ascites carcinoma to host tissues

  • Pierre Mermier
  • Nome Baker
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Abstract

The recovery of [9.10-3H] palmitate complexed to mouse serum albumin was studied 5 sec after ip injection into mice bearing Ehrlich ascites carcinomas. Only about 55% of the injected radioactivity remained in the tumor cells, tumor extracellular fluid and peritoneal washings in mice having ca. 5 ml of the ascites tumor (cells plus extracellular fluid). However the recoveries were nearly quantitative from tumors of larger volume (≥8 ml). A model is proposed to account for the volume-dependent transfer of palmitate from tumor to host in these cancerous mice.

Keywords

Free Fatty Acid Palmitate Peritoneal Cavity Ascitic Fluid Ehrlich Ascites Carcinoma 

References

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Copyright information

© American Oil Chemists’ Society 1973

Authors and Affiliations

  • Pierre Mermier
    • 1
    • 2
  • Nome Baker
    • 1
    • 2
  1. 1.Radioisotope Research Veterans AdministrationWadsworth Hospital CenterLos Angeles
  2. 2.Department of MedicineUCLA School of MedicineLos Angeles

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