, Volume 8, Issue 9, pp 517–521 | Cite as

Sphingolipid fatty acid composition of rat brain “membranous sacs”

  • S. Raghaven
  • C. Spielvogel
  • J. N. Kanfer


A fraction enriched in “membranous sacs” was isolated from the brains of young rats. Ceramide, glucosylceramide, galactosylceramide, lactosylceramide, sulfatide, sphingomyelin and ganglioside were purified. The fatty acids of the individual compounds were identified after hydrolysis. Certain similarities and dissimilarities were observed.


Ceramide Hydroxy Fatty Acid Preparative Thin Layer Chromatography Silicic Acid Column Methyl Glycoside 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Cleland, W.W., and E.P. Kennedy, J. Biol. Chem. 235:45 (1960).PubMedGoogle Scholar
  2. 2.
    Kanfer, J.N., Chem. Phys. Lipids 5:159 (1970).PubMedCrossRefGoogle Scholar
  3. 3.
    Kanfer, J.N. Lipids 4:163 (1969).PubMedCrossRefGoogle Scholar
  4. 4.
    Vanier, M.T., M. Holm, R. Ohman and L. Svennerholm, J. Neurochem. 18:581 (1971).PubMedGoogle Scholar
  5. 5.
    Holm, M.R., Ibid. 15:821 (1968).CrossRefGoogle Scholar
  6. 6.
    Vance, D.E., and C.C. Sweeley, J. Lipid Res. 8:621 (1967).PubMedGoogle Scholar
  7. 7.
    Abramson, M.B., W.T. Norton and R. Katzman, J. Biol. Chem. 240:2389 (1965).PubMedGoogle Scholar
  8. 8.
    Young, O., and J.N. Kanfer, J. Chromatogr. 19:611 (1965).PubMedCrossRefGoogle Scholar
  9. 9.
    Nagai, Y., and J.N. Kanfer, J. Lipid Res. 12:143 (1971).PubMedGoogle Scholar
  10. 10.
    Svennerholm, L., in “Comprehensive Biochemistry,” Vol. 18, Edited by M. Florkin and E.H. Stotz, Elsevier Publishing Co., Amsterdam, 1970, p. 201.Google Scholar
  11. 11.
    Kanfer, J.N., and A.E. Gal, Biochem. Biophys. Res. Commun. 22:442 (1966).CrossRefGoogle Scholar
  12. 12.
    Kanfer, J.N., R.N. Bradley and A.E. Gal, J. Neurochem. 14:1095 (1967).PubMedCrossRefGoogle Scholar
  13. 13.
    Radin, N.S., Adv. Exp. Med. Biol. 19:475 (1972).Google Scholar
  14. 14.
    Brady, R.O., J. Biol. Chem. 237:2416 (1962).PubMedGoogle Scholar
  15. 15.
    Hammerstrom, S., FEBS Lett. 21:259 (1972).CrossRefGoogle Scholar

Copyright information

© American Oil Chemists’ Society 1973

Authors and Affiliations

  • S. Raghaven
    • 1
    • 2
  • C. Spielvogel
    • 1
    • 2
  • J. N. Kanfer
    • 1
    • 2
  1. 1.E.K. Shriver Center at the W.E. Fernald State SchoolWaltham
  2. 2.Neurology Research Massachusetts General HospitalBoston

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