, Volume 2, Issue 5, pp 397–402 | Cite as

Digestion of butyrate glycerides by pancreatic lipase

  • J. Sampugna
  • J. G. Quinn
  • R. E. Pitas
  • D. L. Carpenter
  • R. G. Jensen


The racemic triglycerides, glyceryl-1-palmitate-2,3-dibutyrate (PBB), glyceryl-1-butyrate-2,3-dipalmitate (PPB), glyceryl-2-butyrate-1,3-dipalmitate (PBP), and the diglyceride, racemic glyceryl-1-palmitate-3-butyrate (P-B) were synthesized and digested with pancreatic lipase. Each triglyceride was mixed with equimolar amounts of triolein (OOO) prior to incubation.

The following order of digestion rates was observed: PBB>PPB>PBP>P-B. There was no evidence for short-chain fatty acid specificity; however the triglycerides containing butyric acid were hydrolyzed more rapidly than OOO. Based upon the fatty acid composition of partial glycerides, digestion of butyrate glycerides was not a simple phenomenon. For example, in the digestion of PBB, butyric acid accumulated faster than palmitic acid in the diglycerides, and monobutyrin was found to accumulate when the diglyceride, P-B, was digested. As evidenced by the fatty acid composition of the monoglycerides, positional specificity of pancreatic lipase was always maintained.


Lipase Free Fatty Acid Butyrate Glyceride Butyric Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© American Oil Chemists’ Society 1967

Authors and Affiliations

  • J. Sampugna
    • 1
  • J. G. Quinn
    • 1
  • R. E. Pitas
    • 1
  • D. L. Carpenter
    • 1
  • R. G. Jensen
    • 1
  1. 1.Department of Animal IndustriesUniversity of ConnecticutStorrs

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