Abstract
The fatty acid composition in the adipose tissue of 38 electrocardiographycally confirmed coronary males, mean age 43.7 years, at ideal weight on a 30%-of-calories controlled-fat diet, containing approximately 11.4% of calories as linoleic acid, was studied. The initial linoleic acid concentration in the adipose tissue was approximately 11 mole % of total fatty acids; for approximately the first 12 months it rose slightly and then rapidly increased to about 20% after 24 months. The overall response is sigmoidal in form and fits the equation: 1/y=0.025+0.066 (0.975)x in which y represents the adipose tissue linoleate as mole percentage of total adipose tissue fatty acids and x is the time in months.
The relative increase in linoleic acid is not attributable to a decrease in any specific fatty acid.
Similar content being viewed by others
References
Scott, R. F., K. T. Lee, D. M. Kim, E. S. Morrison and F. Goodale, Amer. J. Clin. Nutr.14, 280–290 (1964).
Kingsbury, K. J., T. D. Heyes, D. M. Morgan, C. Aylott, P. A. Burton, R. Emmerson and P. J. A. Robinson, Biochem. J.84, 124–133 (1962).
Hirsch, J., J. W. Farquhar, E. H. Ahrens, Jr., M. L. Peterson and W. Stoffel, Amer. J. Clin. Nutr.8, 499–511 (1960).
Bierenbaum, M. L., D. P. Green, A. B. Caldwell and E. H. Kelly, J. Med. Soc. New Jersey58, 134–138 (1961).
Fleischman, A. I., A. Florin, J. Fitzgerald, A. B. Caldwell and G. Eastwood, J. Amer. Dietet. Assoc.42, 394–398 (1963).
Fleischman, A. I., T. Hayton and M. L. Bierenbaum, Amer. J. Clin. Nutr.15, 299–302 (1964).
Fleischman, A. I., T. Hayton and M. L. Bierenbaum, Amer. J. Clin. Nutr.20, 333–337 (1965).
Gordis, E., J. Clin. Invest.44, 1978–1985 (1965).
Privett, O. S., M. L. Blank and B. Verdino, J. Nutr.85, 187–195 (1965).
Author information
Authors and Affiliations
About this article
Cite this article
Fleischman, A.I., Hayton, T., Bierenbaum, M.L. et al. The effect of a polyunsaturated diet upon adipose-tissue fatty acids in young coronary males. A five-year cohort study. Lipids 3, 147–150 (1968). https://doi.org/10.1007/BF02531732
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02531732