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Lipids

, Volume 1, Issue 4, pp 237–240 | Cite as

Lipid synthesis in peripheral nerve from alloxan diabetic rats

  • Sven G. Eliasson
Article

Abstract

Decreased conduction velocity in the peripheral nerves of rats is noted after induction of diabetes. The slowing of nerve conduction is accompanied by a decrease in the in vitro incorporation of radioactive precursors into some of the myelin lipids isolated from nerve segments. Cerebroside synthesis is more depressed than that of any other fraction. A change in the type of cerebrosides synthesized is seen with a pronounced decrease in the rate of incorporation of saturated fatty acids.

Keywords

Sciatic Nerve Alloxan Nerve Segment Mercuric Acetate Normal Fatty Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© American Oil Chemists’ Society 1966

Authors and Affiliations

  • Sven G. Eliasson
    • 1
    • 2
  1. 1.Department of NeurologyWashington University, School of MedicineSt. Louis
  2. 2.The Beaumont-May Institute of NeurologyWashington University, School of MedicineSt. Louis

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