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On the rate of cholesterol esterification in cord blood serum

  • Published:
Lipids

Abstract

Cholesterol esterification was studied in adult and cord serum by measureing the initial rate of lecithin-cholesterol acyl transferase (LCAT) activity. Cord serum had about one-third as much free and esterified cholesterol and about one-half as much LCAT as adult serum. When the adult LCAT activities are plotted against the individual's serum free cholesterol levels a straight line relationship results (0.101±.005% cholesterol esterified per min). Cord serum LCAT activities (.135±.0407% cholesterol esterified per min) in the main fall above the adult line. Our results show that cord serum can esterify cholesterol at a rate equal to or higher than adult serum when the LCAT activity is related to the amount of serum free cholesterol present.

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Authors and Affiliations

  1. Division of Cardiology, Department of Medicine and the Fels Research Institute, Temple University Health Sciences Center, 19140, Philadelphia, Pennsylvania

    Andras G. Lacko, Harold L. Rutenberg & Louis A. Soloff

Authors
  1. Andras G. Lacko
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  2. Harold L. Rutenberg
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  3. Louis A. Soloff
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Lacko, A.G., Rutenberg, H.L. & Soloff, L.A. On the rate of cholesterol esterification in cord blood serum. Lipids 7, 426–429 (1972). https://doi.org/10.1007/BF02531515

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  • DOI: https://doi.org/10.1007/BF02531515

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