Lipids

, Volume 6, Issue 2, pp 139–141 | Cite as

Potential function of cholesterol in blood coagulation: Amplification of phospholipid thromboplastic activity

  • Oyvind Sorbye
  • Fred C. Phillips
  • W. O. Lundberg
Short Communications

Abstract

Recalcification tests have revealed a two- to threefold increase in the thromboplastic activity of recombined phospholipid fractions from chicken erythrocyte lipids on supplementation with the original concentration of cholesterol. An optimal four- to fivefold increase was obtained at higher levels. Cholesterol esters had no such effect and clotting times with Russell’s viper venom were not similarly affected.

Keywords

Cholesterol Ester Erythrocyte Lipid Unsaturated Species Pure Cholesterol Chicken Plasma 

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Copyright information

© American Oil Chemists’ Society 1971

Authors and Affiliations

  • Oyvind Sorbye
    • 1
  • Fred C. Phillips
    • 1
  • W. O. Lundberg
    • 1
  1. 1.The Hormel InstituteUniversity of MinnesotaAustin

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