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Net esterification in vitro of plasma cholesterol in human primary hyperlipidemia

  • Published:
Lipids

Abstract

Net esterification of cholesterol was studied in vitro in the plasma of normal subjects and of patients with different types of hyperlipidemia. Net esterification of cholesterol was found to be significantly enhanced in types IIa, IV and V of human primary hyperlipidemia. In the plasma of all normal and hyperlipidemic subjects taken as a group, net esterification of cholesterol is significantly correlated with free cholesterol (p<0.001) and with phosphatidyl choline (p<0.001).

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References

  1. Glomset, J.A., J. Lipid Res. 9:155 (1968).

    PubMed  CAS  Google Scholar 

  2. Shapiro, I.L., J.A. Jastremsky and D. Kritchevsky, Lipids 3:381 (1968).

    CAS  PubMed  Google Scholar 

  3. Monger, E.A., and P.J. Nestel, Clin. Chim. Acta 15:269 (1967).

    Article  CAS  Google Scholar 

  4. Fredrickson, D.S., R.I. Levy and R.S. Lees, New England J. Med. 276:32, 94, 148, 215, 273 (1967).

    Google Scholar 

  5. Glomset, J.A., E.T. Janssen, R. Kennedy and J. Dobbins, J. Lipid Res. 7:638 (1966).

    PubMed  CAS  Google Scholar 

  6. Akanuma, Y., and J.A. Glomset, J. Lipid Res. 9:620 (1968).

    PubMed  CAS  Google Scholar 

  7. Lees, R.S., and F.T. Hatch, J. Lab. Clin. Med. 61:518 (1963).

    PubMed  CAS  Google Scholar 

  8. Block, W.D., K.J. Jarret and L.B. Levine, Clin. Chem. 12:681 (1966).

    PubMed  CAS  Google Scholar 

  9. Sperry, W.M., and M. Webb, J. Biol. Chem. 187:97 (1950).

    PubMed  CAS  Google Scholar 

  10. Kraml, M., and L. Cosyns, Clin. Biochem. 2:373 (1969).

    Article  CAS  Google Scholar 

  11. Bligh, E.G., and W.J. Dyers, Can. J. Biochem. Physiol. 37:911 (1959).

    PubMed  CAS  Google Scholar 

  12. Bartlett, G.R., J. Biol. Chem. 234:466 (1959).

    PubMed  CAS  Google Scholar 

  13. Porte, Jr., D., and R.J. Havel, J. Lipid Res. 2:357 (1961).

    CAS  Google Scholar 

  14. Portman, O.W., and M. Sugano, Arch. Biochem. Biophys. 105:532 (1964).

    Article  PubMed  CAS  Google Scholar 

  15. Stokke, K.T., and K.R. Norum, Scand. J. Clin. Lab. Invest. 27:21 (1971).

    PubMed  CAS  Google Scholar 

  16. Rose, H.G., Biochim. Biophys. Acta 152:728 (1968).

    PubMed  CAS  Google Scholar 

  17. Glomset, J.A., and J.L. Wright, Biochim. Biophys. Acta 89:266 (1964).

    PubMed  CAS  Google Scholar 

  18. Bragdon, J.H., R.J. Havel and E. Boyle, J. Lab. Clin. Med. 48:36 (1956).

    PubMed  CAS  Google Scholar 

  19. Fredrickson, D.S. in “The Metabolic Basis of Inherited Diseases,” Edited by J.B. Stanbury, J.B. Wyngaarden and D.S. Fredrickson, McGraw Hill, New York, 1960, p. 505.

    Google Scholar 

  20. Glomset, J.A., K.R. Norum and W. King, J. Clin. Invest. 49:1827 (1970).

    Article  PubMed  CAS  Google Scholar 

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Marcel, Y.L., Fabien, H.D. & Davignon, J. Net esterification in vitro of plasma cholesterol in human primary hyperlipidemia. Lipids 6, 722–726 (1971). https://doi.org/10.1007/BF02531297

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  • DOI: https://doi.org/10.1007/BF02531297

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