Lipids

, Volume 6, Issue 11, pp 836–843 | Cite as

Isolation and identification of cholesterol α-oxide and other minor sterols in human serum

  • M. F. Gray
  • T. D. V. Lawrie
  • C. J. W. Brooks
Article

Abstract

The isolation and identification of cholesterol α-oxide, coprostanol, β-sitosterol, cholest-4-en-3-one and cholesta-4, 6-dien-3-one from human serum are reported. Compounds were isolated by thin layer chromatography and were identified by gas liquid chromatography and gas chromatography-mass spectrometry (GC-MS). Data for standard sterols are also reported. The possible origins of these minor components and the significance of their presence are discussed.

Keywords

Salen Sitosterol Lanosterol Sterol Ester Free Sterol 

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Copyright information

© American Oil Chemists’ Society 1971

Authors and Affiliations

  • M. F. Gray
    • 1
  • T. D. V. Lawrie
    • 1
  • C. J. W. Brooks
    • 2
  1. 1.Department of Medical CardiologyUniversity of GlasgowGlasgow
  2. 2.Department of ChemistryUniversity of GlasgowGlasgow

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