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Hierachical classification of physiologically active substances

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Abstract

In a first attempt at a hierarchical classification of physiologically active substances, these substances were divided into two classes corresponding to their effect on the main cellular signaling systems. That some general principles of the chemical structure of drugs do exist has been demonstrated using quantum chemistry methods, artificial intelligence, and biophysical approaches.

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Authors
  1. A. I. Luik
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Additional information

Institute of Bioorganic and Petroleum Chemistry, National Academy of Sciences of Ukraine, 1 Murmanskaya ul., Kiev 253094, Ukraine. Translated from Teoreticheskaya i Éksperimental'naya Khimiya, Vol. 34, No. 4, pp. 199–213, July–August, 1998.

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Luik, A.I. Hierachical classification of physiologically active substances. Theor Exp Chem 34, 177–190 (1998). https://doi.org/10.1007/BF02523248

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  • DOI: https://doi.org/10.1007/BF02523248

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