Advertisement

Electrostatic charge characteristics of Der p1 allergen-carrying particles and the house dust mitedermatophagoides pteronyssinus

  • P. T. Gaynor
  • J. F. Hughes
Communication

Abstract

Control of the house dust mite allergen has received considerable attention owing to its importance in some allergic diseases. One aspect of dust mites and their allergen-carrying faecal particles that has not been reported on, which may have allergen control applications, is the electrostatic charge they carry in the natural environment. To promote tribo-electric charging, household dust containing dust mite allergen and live house dust mites are separately agitated while in contact with either polypropylene, nylon or earthed metal. The charged dust and mites are subsequently subjected to electrostatic separation and collection. Results for concentrations of the house dust mite allergen, Der p1, indicate that, when subjected to nylon, Der p1 carrier particles appear to be predominantly positively charged. Similarly, when subjected to polypropylene, Der p1 carrier particles also appear to be positively charged. Reduction of excess free charge by agitation against earthed metal does not appear to affect the observed charging characteristics, indicating that the positive charge may be bound or inherent in the Der p1 carrier particles. In contrast, house dust mites exposed to nylon appear to be generally charging negative, whereas mites exposed to polypropylene appear to be charging positive. The observed electrostatic characteristics of the mites and Der p1 carrying particles will be useful in the future development of electrostatic allergen control methods.

Keywords

House dust mite Electrostatic charge Der p1 Allergen Electrostatic control Dermatophagoides pteronyssinus 

References

  1. Brown, M. A., Halonen, M. J. andMartinez, F. D. (1997): ‘Cutting the cord: is birth already too late for primary prevention of allergy?’,Clin. Exp. Allergy,27, pp. 4–6CrossRefGoogle Scholar
  2. Colin, M. E., Richard, D., Fourcassie, V. andBelzunces, L. P. (1992): ‘Attraction of Varroa Jacobsoni, parasite of Apis mellifera by electrical charges’,J. Insect Physiol.,38, pp. 111–117CrossRefGoogle Scholar
  3. Colloff, M. J., Ayres, J., Carswell, F., Howarth, P. H., Merrett, T. G., Mitchell, E. B., Walshaw, M. J., Warner, J. O., Warner, J. A. andWoodcock, A. A. (1992): ‘The control of allergens of dust mites and domestic pets: a position paper’,Clin. Exp. Allergy 22, (2), pp. 1–28CrossRefGoogle Scholar
  4. Cross, J. A. (1987). ‘Electrostatics: principles, problems and applications’ (Adam Hilger Ltd, Bristol)Google Scholar
  5. Hide, D. W. (1995): ‘Allergy prevention— An attainable objective?’Eur. J. Clin. Nutrit.,49, (1), pp. S71-S76Google Scholar
  6. Hilczer, B. andMalecki, J. (1986): ‘Electrets’ (Elsevier Science Publishers, Amsterdam)Google Scholar
  7. Piccinni, M. P., Mecacci, F., Sampognaro, S., Manetti, R., Parronchi, P., Maggi, E. andRomagnani, S. (1993): ‘Aero-allergen sensitization can occur during fetal life’,Int. Arch. Allergy Immunol.,102, pp. 301–303CrossRefGoogle Scholar
  8. Platts-Mills, T. A. E., Heyman, P. W., Longbottom, J. L. andWilkins, S. R. (1986): ‘Airborne allergens associated with asthma: Particle sizes carrying dust mite and rate allergens measured with a cascade impactor’,J. Allergy Clin. Immunol.,77, pp. 850–857CrossRefGoogle Scholar
  9. Taylor, D. M. andSecker, P. E. (1994): ‘Industrial electrostatics: fundamentals and measurements’ (John Wiley & Sons Ltd, Chichester)Google Scholar
  10. Tovey, E. R., Chapman, M. D. andPlatts-Mills, T. A. E. (1981): ‘Mite faeces are a major source of house dust allergens’,Nature,289, pp. 592–593CrossRefGoogle Scholar
  11. Tovey, E. R. (1992): ‘Allergen exposure and control’,Exp. Appl. Acarol.,16, pp. 181–202CrossRefGoogle Scholar
  12. Warner, J. A., Miles, E. A., Jones, A. C., Quint, D. J., Colwell, B. M. andWarner, J. O. (1994): ‘Is deficiency of interferon gamma production by allergen triggered cord blood cells a predictor of atopic eczema?’,Clin. Exp. Allergy,24, pp. 423–430CrossRefGoogle Scholar

Copyright information

© IFMBE 1998

Authors and Affiliations

  1. 1.Bioelectrostatics Research CentreUniversity of SouthamptonHighfieldUK

Personalised recommendations