Skip to main content
Log in

Multivariate discriminant analysis of the electromyographic interference pattern: statistical approach to discrimination among controls, myopathies and neuropathies

  • Physiological Measurement
  • Published:
Medical and Biological Engineering and Computing Aims and scope Submit manuscript

Abstract

The stepwise linear discriminant analysis method is used to develop optimal combinations of features measured from the electromyographic interference pattern, with the aim of minimising the miscalassification rate in controls while maximising the correct classification rates in patients with disease. This discriminant analysis among multiple groups leads to the determination of the optimal discriminating surface in a multivariable space and can also produce a severity of disease likelihood index. Applying these combinations of features to 186 studies performed in the biceps muscle, 81% of all studies are accurately classified as being normal, myopathic or neuropathic. An algorithm to perform this stepwise multigroup linear discriminant analysis is described.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Afifi, A. A. (1972): ‘Statistical analysis, a computer oriented approach’ (Academic Press, New York)

    MATH  Google Scholar 

  • Berzuini, C., Figini, M. M., andBernardinelli, L. (1985): ‘Evaluation of the effectiveness of EMG parameters in the study of neurogenic diseases—a statistical approach using clinical and simulated data’,IEEE Trans.,BME-32, pp. 15–27

    Google Scholar 

  • Cacoullos, T. (1973): ‘Discriminant analysis and application’ (Academic Press, New York)

    Google Scholar 

  • Chatfield, C., andCollins, A. J. (1980): ‘Introduction to multivariate analysis’ (Chapman and Hall Inc., New York)

    MATH  Google Scholar 

  • Cooley, W. W. andLohnes, P. R. (1971): ‘Multivariate data analysis’ (John Wiley & Sonc, Inc.)

  • Dillon, W. R., andGoldstein, M. (1984): ‘Multivariate analysis-method and applications’ (John Wiley & Sons, New York)

    Google Scholar 

  • Everitt, B. S. (1989): ‘Statistical methods for medical investigations’ (Oxford University Press, New York)

    Google Scholar 

  • Fisher, R. A. (1936): ‘The use of multiple measurements in taxonomic problems,’Ann. Eugenics,7, pp. 179–188

    Google Scholar 

  • Fuglsang-Frdericksen, A., Scheel, U., andBuchthal, F. (1976): ‘Diagnostic yield of the pattern of electrical activity and of individual motor unit potentials in myopathy’,J. Neurol. Neurosurg. Psychiat.,39, pp. 742–750

    Article  Google Scholar 

  • Fuglsang-Fredericksen, A., Scheel, U., andBuchthal, F. (1977): ‘Diagnostic yield of the pattern of electrical activity of muscle and of individual motor unit potentials in neurogenic involvement,-Ibid.,,40, pp. 544–554

    Google Scholar 

  • Mucciardi, A. N., andGose, E. E. (1971): ‘A comparison of seven techniques for choosing subsets of pattern recognition properties’,IEEE Trans.,C-9, pp. 1023–1031

    Google Scholar 

  • Nandedkar, S. D., Sånders, D. B., andStålberg, E. V. (1986a): ‘Automatic analysis of the electromyographic interference pattern. Part I: Development of quantitative features’,Muscle Nerve,9, pp. 431–439

    Article  Google Scholar 

  • Nandedkar, S. D., Sanders, D. B., andStålberg, E. V. (1986b): ‘Automatic analysis of the electromyographic interference pattern. Part II: Findings in control subjects and in some neuromuscular diseases’,-Ibid.,,9, pp. 491–500

    Article  Google Scholar 

  • Nandedkar, S. D., Sanders, D. B., andStålberg, E. V. (1986c): ‘Simulation and analysis of the electromyographic interference pattern in normal muscle. Part I: Turns and amplitude measurement’,-Ibid.,,9, 419–426

    Google Scholar 

  • Nandedkar, S. D., Sanders, D. B., andStålberg, E. V. (1986d): ‘Simulation and analysis of the electromyographic interference pattern in normal muscle. Part II: Activity, upper centile amplitude and number of small segments’,-Ibid.,,9, pp. 486–496

    Article  Google Scholar 

  • Pratt, J. W., Raiffa, H., andSchlaifer, R. (1995): ‘Introduction to statistical decision theory’ (MIT Press, Cambridge, Massachusetts)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cao, J., Sanders, D.B. Multivariate discriminant analysis of the electromyographic interference pattern: statistical approach to discrimination among controls, myopathies and neuropathies. Med. Biol. Eng. Comput. 34, 369–374 (1996). https://doi.org/10.1007/BF02520008

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02520008

Keywords

Navigation