Journal of Radioanalytical Chemistry

, Volume 37, Issue 2, pp 523–528 | Cite as

A study of lithium uptake and location in the brain using the nuclear track technique

  • B. S. Carpenter
  • D. Samuel
  • I. Wassermann
  • A. Yuwiller
Biological and Biomedical Applications (Cont.)

Abstract

The nuclear track technique was used to study the lithium uptake and location in the brains of rats. This study indicated that a maximum lithium concentration was reached in the brain eight hours after an intraperitoneal injection.

Keywords

Lithium Lithium Treatment Lithium Concentration Track Density Lithium Salt 

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References

  1. 1.
    S. GERSON, B. SHOPSIN, Eds., Lithium, Its Role in Psychiatric Treatment and Research, Plenum Press, 1973.Google Scholar
  2. 2.
    F. N. JOHNSON, Ed., Lithium Research and Therapy, Academic Press, 1974.Google Scholar
  3. 3.
    D. SAMUEL, Z. GOTTESFELD, Endeavour, 32 (1973) 122.Google Scholar
  4. 4.
    B. S. CARPENTER, D. SAMUEL, I. WASSERMANN, ANS Transactions, 18 (1974) 85.Google Scholar
  5. 5.
    R. L. FLEISCHER, P. B. PRICE, R. M. WALKER, Nuclear Tracks in Solids. Principles and Applications, University of California Press, 1975.Google Scholar
  6. 6.
    P. J. TALSO, R. W. CLARKE, Am. J. Physiol., 166 (1951) 202.Google Scholar
  7. 7.
    J. FOULKS, G. H. MUDGE, A. GILMAN, Am. J. Physiol., 163 (1952) 642.Google Scholar
  8. 8.
    M. S. EBADI, V. J. SIMMONS, M. J. HENDRICKSON, P. S. LACY, J. Pharm., 27 (1974) 342.Google Scholar
  9. 9.
    J. M. MORRISON, H. D. PRITCHARD, M. C. BRAUDE, W. D’AGUANNO, Proc. Soc. Exptl. Biol. Med., 137 (1971) 889.Google Scholar
  10. 10.
    P. A. BOND, B. A. BROOKS, A. JUDD, British J. Pharmacology, 53 (1975) 155.Google Scholar
  11. 11.
    R. I. FRANCIS, M. A. TRAILL, Lancet 2 (1970) 523.CrossRefGoogle Scholar

Copyright information

© Akadémiai Kiadó 1977

Authors and Affiliations

  • B. S. Carpenter
    • 1
  • D. Samuel
    • 2
  • I. Wassermann
    • 2
  • A. Yuwiller
    • 3
    • 4
  1. 1.Analytical Chemistry DivisionNational Bureau of StandardsWashington, D. C.USA
  2. 2.Weizmann Institute of ScienceRehovotIsrael
  3. 3.Neurobiochemistry Laboratory T-85Brentwood Veterans Administration HospitalLos AngelesUSA
  4. 4.The Department of Psychiatry and The Brain Research InstituteUCLALos AngelesUSA

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