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Hippuran-123I: Preparation and quality control

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Abstract

A kit-like procedure is described for the labelling of Hippuran by exchange in a melt with carrier-free iodide-123 directly formed from the decay of123Xe. Decay and subsequent melting for 15 min at 180°C are performed in one and the same ampoule. This results in a transfer of 95% of the123I-activity into Hippuran with a residual123I-content of <1.0%. Quality control is based on thin-layer chromatography. Contaminants are discussed and a comparison is made with commercial preparations of Hippuran-131I.

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Authors and Affiliations

  1. Institut voor Kernphysisch Onderzoek (IKO), Amsterdam, (The Netherlands)

    J. A. Bijl, F. M. Kaspersen & L. Lindner

Authors
  1. J. A. Bijl
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  2. F. M. Kaspersen
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  3. L. Lindner
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Bijl, J.A., Kaspersen, F.M. & Lindner, L. Hippuran-123I: Preparation and quality control. J. Radioanal. Chem. 35, 55–62 (1977). https://doi.org/10.1007/BF02518212

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  • DOI: https://doi.org/10.1007/BF02518212

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