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Moderate antioxidative efficiencies of flavonoids during peroxidation of methyl linoleate in homogeneous and micellar solutions

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Journal of the American Oil Chemists’ Society

Abstract

The relative reactivities as well as the stoichiometric coefficients for a number of flavonoids, catechols, and—for comparison—standard phenolic antioxidants were determined by analyzing the kinetics of oxygen consumption in organic and micellar systems, with peroxidation initiated by lipid- and water-soluble azo initiators. The results demonstrated that the flavonoids did not behave as classic phenolic antioxidants such as α-tocopherol, but showed only moderate chain-breaking activities. The results were in line with other structure-activity relationship studies on the importance of the B-ring catechol structure, the 2,3-double bond, and the 3,5-hydroxy groups. The data are discussed in view of possible explanations of the deviations flavonoids reveal in their behavior compared with regular phenolic antioxidants.

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Authors and Affiliations

  1. N.N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Kosygin St. 4, Moscow, Russia

    V. A. Roginsky, T. K. Barsukova & A. A. Remorova

  2. Institut für Strahlenbiologie, GSF Research Center Neuherberg, 85758, Oberschleissheim, Germany

    W. Bors

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  1. V. A. Roginsky
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  2. T. K. Barsukova
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  3. A. A. Remorova
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  4. W. Bors
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Roginsky, V.A., Barsukova, T.K., Remorova, A.A. et al. Moderate antioxidative efficiencies of flavonoids during peroxidation of methyl linoleate in homogeneous and micellar solutions. J Am Oil Chem Soc 73, 777–786 (1996). https://doi.org/10.1007/BF02517955

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  • DOI: https://doi.org/10.1007/BF02517955

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