Journal of Radioanalytical Chemistry

, Volume 53, Issue 1–2, pp 291–298 | Cite as

The kinetics of incorporation of111In into m-tetraphenylporphine

  • A. D. Nunn
Medical Radionuclides and the Quality of Radiopharmaceuticals

Abstract

An improved method is described for rapidly incorporating “carrier-free”111In into m-tetraphenylporphine to produce a lipid soluble complex of potential clinical usefulness. The reaction in glacial acetic acid is temperature dependent and markedly sensitive to the nature of the anion present. Halide ions completely inhibit incorporation of the111In. An unusual destruction of the porphyrin ring by nitrate in glacial acetic acid is reported.

Keywords

Porphyrin Glacial Acetic Acid Macrocyclic Ligand Indium Atom Metalloporphyrin 

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Copyright information

© Akadémiai Kiadó 1979

Authors and Affiliations

  • A. D. Nunn
    • 1
  1. 1.Division of Nuclear MedicineUpstate Medical CenterSyracuseUSA

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