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The kinetics of incorporation of111In into m-tetraphenylporphine

  • Medical Radionuclides and the Quality of Radiopharmaceuticals
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Abstract

An improved method is described for rapidly incorporating “carrier-free”111In into m-tetraphenylporphine to produce a lipid soluble complex of potential clinical usefulness. The reaction in glacial acetic acid is temperature dependent and markedly sensitive to the nature of the anion present. Halide ions completely inhibit incorporation of the111In. An unusual destruction of the porphyrin ring by nitrate in glacial acetic acid is reported.

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Author notes

  1. A. D. Nunn

    Present address: E. R. Soluibb and Sons, Georges Rd., 08903, New Brunswik, N. J., USA

Authors and Affiliations

  1. Division of Nuclear Medicine, Upstate Medical Center, 13210, Syracuse, New York, USA

    A. D. Nunn

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  1. A. D. Nunn
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Nunn, A.D. The kinetics of incorporation of111In into m-tetraphenylporphine. J. Radioanal. Chem. 53, 291–298 (1979). https://doi.org/10.1007/BF02517927

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  • DOI: https://doi.org/10.1007/BF02517927

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