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[14α, 15α-3H] steroids for pharmacological research

  • Labelled Compounds
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Abstract

It is shown in the present work that the labelling of steroids in ring D is suitable for the production of stable compounds. Two syntheses are described. The final products represent the tritium labelled forms of two pharmacologically important 4,9-dienones with high radiochemical purity. Unfortunately, these dienones are very sensitive to self-radiolysis. They must be stored as diluted solutions at low temperature.

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References

  1. K. PONSOLD, J. RÖMER, H. WAGNER, J. Lab. Comp., 10 (1974) 533.

    Article  CAS  Google Scholar 

  2. J. RÖMER, S. SCHWARZ, G. WEBER, J. Lab. Comp Radiopharm., 18 (1981) 1295.

    Article  Google Scholar 

  3. H. WAGNER, J. RÖMER, H. KASCH, J. Lab. Comp. Radiopharm., 18 (1981) 1611.

    Article  CAS  Google Scholar 

  4. M. HÜBNER et. al., Arzneimittelforschung, 30 (1980) 401.

    Google Scholar 

  5. H. SMITH et. al., Experientia, 19 (1963) 394.

    Article  CAS  Google Scholar 

  6. H. WAGNER, J. RÖMER, M. HÜBNER, WP C 07 j/213882 (1979).

  7. J. RÖMER et. al., J. Lab. Comp. Radiopharm., 19 (1982) 855.

    Article  Google Scholar 

  8. J. RÖMER, H. WAGNER, Zfk-Report 356 (1978).

  9. H. WAGNER, et. al., J. Lab. Comp. Radiopharm., 17 (1980) 317.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Central Institute of Nuclear Research, Rossendorf, 8051, Dresden, (GDR)

    J. Römer

  2. Central Institute of Microbiology, 69, Jena, (GDR)

    H. Wagner

Authors
  1. J. Römer
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  2. H. Wagner
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Römer, J., Wagner, H. [14α, 15α-3H] steroids for pharmacological research. J. Radioanal. Chem. 80, 217–221 (1983). https://doi.org/10.1007/BF02517665

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  • DOI: https://doi.org/10.1007/BF02517665

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