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Simultaneous determination of35S and14C in double-labelled organic compounds by liquid scintillation counting

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Abstract

An isotope analytical method for the simultaneous determination of35S and14C in double-labelled organic compounds by liquid scintillation counting is described. The sample is burned in a stream of oxygen. Sulfur oxides are converted to sulfuric acid and separated from other combustion products, including carbon-14 dioxide, on a heated quartz wool column previously wetted with hydrogen peroxide. Carbon dioxide is collected from the gas stream by an absorbent suitable for liquid scintillation counting. The residual sulfuric acid is rinsed off the column with water and the aqueous solution obtained is mixed with a liquid scintillation cocktail for radioactivity measurement. The final solutions ready for counting are obtained in less than fifteen minutes, quantitative collection recovery is achieved and no cross contamination occurs.

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References

  1. R. TYKVA, V. PANEK, Radiochem. Radional. Letters, 14 (1973) 109.

    CAS  Google Scholar 

  2. A. JEFFAY, J. ALVAREZ, Anal. Biochem., 2 (1961) 507.

    Article  Google Scholar 

  3. G. KAINZ, E. WACHBERGER, Z. Anal. Chem., 222 (1966) 10.

    Article  Google Scholar 

  4. M. F. BARAKAT, M. ABDEL-GHANY, Microchem. J., 15 (1970) 184.

    Article  CAS  Google Scholar 

  5. R. BELCHER, J. E. FILDES, A. J. NUTTEN, Anal. Chim. Acta, 13 (1955) 431.

    Article  CAS  Google Scholar 

  6. Y. A. GAWARGIOUS, A. M. G. MACDONALD, Anal. Chim. Acta, 27 (1962) 119.

    Article  CAS  Google Scholar 

  7. I. GÁCS, Z. VARGAY, J. CSETENYI, Mikrochim. Acta, (1977) 107.

  8. I. GÁCS, S. DOMBI, J. Radional. Chem., 42 (1978) 375.

    Google Scholar 

  9. T. SZARVAS, Cs. ÖMBÖLY, G. VÉGH, Radioisotopy, 12 (1971) 779.

    Google Scholar 

  10. J. B. BUCKLEY, Intern. J. Appl. Radiation Isotopes, 22 (1971) 41.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Central Research Institute for Chemistry of the Hungarian Academy of Sciences, Pusztaszeri út 59-67, 1025, Budapest, Hungary

    I. Gács & S. Dombi

  2. Chinoin Factory for Pharmaceutical and Chemical Products, Budapest, Hungary

    Z. Vargay

Authors
  1. I. Gács
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  2. Z. Vargay
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  3. S. Dombi
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Gács, I., Vargay, Z. & Dombi, S. Simultaneous determination of35S and14C in double-labelled organic compounds by liquid scintillation counting. J. Radioanal. Chem. 45, 15–23 (1978). https://doi.org/10.1007/BF02517106

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  • DOI: https://doi.org/10.1007/BF02517106

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