Abstract
The object of this paper is to give details of a production method for123I, now in routine use at Harwell. We employ the (p, 5n) reaction, irradiating a liquid target of di-iodomethane (CH2I2) spiked with additional iodine, with 58 MeV protons. A yield of ∼9 mCi/μAh is obtained; the only detectable radionuclidic impurity is125I, present to the extent of ∼0.15% by activity at the time of separation of Xe from I.
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M. A. FUSCO, N. F. PEEK, J. A. JUNGERMAN, F. W. ZIELEINSKI, S. J. de NARDO, G. L. de NARDO, J. Nucl. Med., 13 (1972) 430; J. Nucl. Med., 13 (1972) 729 and 13 (1972) 729. M. C. LAGUNAS-SOLAR, J. A. JUNGERMAN, N. F. PEEK, C. W. BENNETT, J. Lab. Cpds. Radiopharm., 16.1 (1979) 224.
E. LOEPFE, I. HUSZAR, F. HEGEDUS, 1st Int. Symp. on Radiopharm. Chem. Brookhaven, Sept. 21–24 1976; Abstract 73.
J. G. CUNINGHAME, J. I. S. HILL, A. L. NICHOLS, N. K. TAYLOR; UKAEA Unclassified Report AERE 9087, 1978.
E. ACERBI, C. BIRATTORI, M. CASTAGLIONI, F. RESMINI, M. VILLA, Int. J. Appl. Radiation Isotopes, 26, (1975) 741.
R. WEINREICH, O. SCHULT, G. STOCKLIN, Int. J. Appl. Radiation Isotope, 25 (1974) 535.
J. G. CUNINGHAME, B. MORRIS, A. L. NICHOLS, N. K. TAYLOR, Int. J. Appl. Radiation Isotope, 27 (1976) 597.
A. M. J. PAANS, W. VAALBURG, G. van HERK, M. G. WOLDRING, Int. J. Appl. Radiation Isotopes, 27 (1976) 465.
D. B. SYME, E. WOOD, I. M. BLAIR, S. KEW, M. PERRY, P. COOPER, UKAEA Unclassified Report AERE 8276, (1976.
S. R. WILKINS, S. T. SHIMOSE, H. H. HINES, J. A. JUNGERMAN, F. HEGEDUS, G. L. de NARDO, Int. J. Appl. Radiation Isotope, 26 (1975) 279.
L. LINDNER, G. A. BRINKMAN, T. H. G. A. SUER, A. SCHIMMEL, J. T. VEENBOER, F. H. S. KARTEN, J. VISSER, C. J. LEURS, Proc. Symp. on Radiopharm. Labelled Comps. Copenhagen 1973; IAEA-SM-171/63.
R. D. ACKLEY, Z. COMBS, USAEC Unclassified Report ORNL-TM-4227, 1973. B. P. K. SHARPE; UKAEA Unclassified Report AERE R-7742, 1974.
A. SCHIMMEL, F. M. KASPARSEN, L. LINDNER, Int. J. Appl. Radiation Isotopes, 30 (1979) 63.
R. BETT, R. CLEGG, J. G. CUNINGHAME, C. DEADMAN, B. GRIEVSON, N. K. TAYLOR UKAEA Unclassified Report AERE R-9448, 1979.
R. BETT, R. CLEGG, J. G. CUNINGHAME, B. GRIEVSON, UKAEA Unclassified Report AERE R-9449, 1979.
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Bett, R., Cuninghame, J.G., Hill, J.I.S. et al. Development of a process for routine production of123I using the127I(p, 5n)123Xe→123I reaction. J. Radioanal. Chem. 56, 237–249 (1980). https://doi.org/10.1007/BF02516956
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DOI: https://doi.org/10.1007/BF02516956