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Production of123I and28Mg by high-energy nuclear reactions for applications in life sciences

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Abstract

The advantages of high energy cyclotrons as compared to small compact cyclotrons for the production of special radionuclides are outlined. The routine production of123I (T=13.3 h) and28Mg (T=21.1 h) by means of high energy nuclear reactions at the Jülich Isochronous Cyclotron is described. The reaction127I(d,6n)123 \(Xe\xrightarrow{{\beta ^ + ,EC}}\) 123I at 78 to 64 MeV is used for the production of123I with thick target yields of 8 mCi/μAh and high radionuclidic purity. The practical experience in the application of this process, which is well suited for the production of Na123I and for123Xe-exposure labelling techniques, is reported.28Mg is produced by the27Al(α, 3p)28Mg reaction at Eα=140 to 30 MeV with thick target yields of 40 μCi/μAh. The carrier-free28Mg is separated from the matrix activities by coprecipitation and anion exchange with chemical yields of 80%.

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Authors and Affiliations

  1. Institut 1: Nuklearchemie, Institut für Chemie der Kernforschungsanlage Jülich GmbH, D-517, Jürlich, (FRG)

    R. Weinreich, S. M. Qaim, H. Michael & G. Stöcklin

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  1. R. Weinreich
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  2. S. M. Qaim
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  3. H. Michael
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  4. G. Stöcklin
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Weinreich, R., Qaim, S.M., Michael, H. et al. Production of123I and28Mg by high-energy nuclear reactions for applications in life sciences. J. Radioanal. Chem. 30, 53–66 (1976). https://doi.org/10.1007/BF02516618

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