Electrical activity of the lateral hypothalamus related to food-procuring movements of rats
On freely moving albino rats we demonstrated that, when fast food-procuring movements are performed, the mass electrical activity of the lateral hypothalamus (LH) is suppressed 1.6–2.0 sec before the movement beginning recorded with a photoelectrical device. Videorecording of the movements and recording of the spike activity of LH units showed that the latter are activated 1.0–0.1 sec before the movement initiation. The LH is considered a motivation-related structure, which serves as a source providing an increase in the excitability of the structures involved in the control of food-procuring movements and, further on, supporting this increased excitability. The LH is also a component of the mechanisms providing formation of the motor program. The role of the LH in the ensemble of motor centers, which organize and control voluntary movements, is discussed.
KeywordsSpike Activity Autonomic Support Lateral Hypothalamus Motor Program Movement Initiation
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- 4.O. G. Baklavadzhyan, A. G. Mkrtchyan, and E. G. Astvatsatryan, “Responses of pyramidal tract neurons and corticorubral neurons to stimulation of different structures of the lateral hypothalamus in cats,”Neirofiziologiya,14, No. 3, 298–306 (1982).Google Scholar
- 5.V. K. Berezovskii, T. G. Kebkalo, and L. A. Savos’kina, “Intrabrainstem afferent connections of the hypothalamic locomotor region of the cat brain,”Neirofiziologiya,16, No. 3, 353–362 (1984).Google Scholar
- 6.N. V. Bratus’ and M. V. Yoltukhovskii, “Electrophysiological analysis of the hypothalamic influences on the cerebellar cortex,”Fiziol. Zh.,32, No. 3, 257–263 (1983).Google Scholar
- 7.V. A. Maiskii,Structural Organization and lintegration of the Descending Neuronal Systems of the Brain and Spinal Cord [in Russian], Naukova Dumka, Kyiv (1983).Google Scholar
- 9.E. K. Davydova and G. A. Grigoryan, “Role of the lateral and medial hypothalamus in reproduction of a motor reaction playing the role of a signal in training of classic conditioned reflexes,”Pavlov Zh. Vyssh. Nerv. Deyat.,41, No. 1, 41–50 (1991).Google Scholar
- 12.M. V. Yoltukhovskii, “Rapid ballistic food-procuring movements in rats: phenomenology and probable mechanisms of control,”Neirofiziologiya/Neurophysiology,29, No. 3, 175–184 (1997).Google Scholar
- 13.V. M. Moroz, M. V. Yoltukhovskii, and O. V. Vlasenko,The Lateral Hypothalamus and Prefrontal Cortex: Their Role in Organization of the Voluntary Movements [in Ukraine], Vinnytsya, Kyiv (1998).Google Scholar
- 14.L. J. Pellegrino, A. S. Pellegrino, and A. J. Cursman,A Stereotaxic Atlas of the Rat Brain, Plenum Press, New York (1979).Google Scholar
- 16.M. V. Yoltukhovskii, “Role of the lateral hypothalamus in organization of rapid ballistic food-procuring movements in rats,”Arkh. Klin. Éksp. Med.,7, No. 1, 72–75 (1998).Google Scholar