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Activity and localization of cerebral cysteinic cathepsins after the action of ionizing radiation

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Abstract

The effect of total X-ray irradiation (0.155 C/kg) on the activity of cathepsin L (KF 3.4.22.15) from the light mitochondrial fraction and microsomal soluble fraction of the gray substance of the neocortex was studied in rats. The estimations were performed 1, 24, 48, and 120 h after irradiation. The changes in the cathepsin L activity observed in acute radiation pathology were complex and multiphasic.

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Chernaya, V.I. Activity and localization of cerebral cysteinic cathepsins after the action of ionizing radiation. Neurophysiology 31, 47–48 (1999). https://doi.org/10.1007/BF02515013

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