Abstract
Pulse radiolysis of MIT and DIT irradiated to doses from 2.8·104 to 85·104 rads is studied by ascending chromatography. The 3-iodo-4,5-dihydroxyphenylalanine (DOPA-I) and 3-iodo-4-hydroxyphenylalanine have been identified as first stages of degradations of MIT and DIT, respectively. G values are 0.015 for MIT (10−5M) and 0.004 for DIT (0.5·10−5M). By self decomposition MIT is degraded less rapidly than DIT and there is no formation of DOPA-I.
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R. J. BAILLY, E. A. EVANS, J. Label. Compounds, 2 (1966) 1.
G. L. FLETCHER, S. OKADA, Radiat. Res., 15 (1961) 349.
J. ROWBOTTOM, J. Biol. Chem., 212 (1955) 877.
O. H. WHEELER, R. MONTALVO, Radiat. Res., 40 (1969) 1.
A. APPLEBY, R. P. UMFRID, J. Label. Compounds, 8 (1972) 415.
M. HAISSINSKI (Ed.), Action chimique et biologique des radiations, Masson et Cie, Paris, 1967.
F. GERARD, Radioprotection, 4 (1969) 279.
M. MAIS, K. MACEK (Eds), Handbuch der Papier Chromatographie, G. Fischer Verlag, Jena, 1958–1960, p. 1343.
L. REIO, J. Chromatog., 47 (1970) 60.
J. ROCHE, R. MITCHEL, S. LISSITSKY, in D. GLICH, Meth. Biochem. Anal., 12 (1964) 156.
F. GADENNE, La radiolyse de la thyroxine. Diplôme d'études supérieures Fac. de Science d'Orsay.
J. D. ROBERTS, M. C. CASEIRO (Eds), Chimie organique moderne, Ediscience, Paris, 1968.
E. FOURNEAU, J. DUREY, Compt. Rend. Acad. Sci., 199 (1934) 870.
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Lambert, F., Frapart, P. & Cohen, Y. Radiolyse de la monoiodotyrosine et de la diiodotyrosine marquees a l'iode-125. J. Radioanal. Chem. 24, 115–124 (1975). https://doi.org/10.1007/BF02514388
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DOI: https://doi.org/10.1007/BF02514388