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Endothelial cells lining polyester fabric express pro-coagulant phenotypein vitro

  • M. Rémy
  • R. Bareille
  • F. Villars
  • F. Rouais
  • A. Gorodkov
  • L. Bordenave
Cellular Engineering

Abstract

The paper deals with the in vitro assessment of endothelial cell (EC) phenotype covering an albumin- and chitosan-coated polyester fabric and shows that resting ECs express a pro-coagulant phenotype by releasing a high von Willebrand factor level and expressing low thrombomodulin surface activity, despite maintaining an adequate response to stimulating agents.

Keywords

Endothelial cell polyester fabric von Willebrand factor Thrombomodulin 

References

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Copyright information

© IFMBE 1998

Authors and Affiliations

  • M. Rémy
    • 1
  • R. Bareille
    • 1
  • F. Villars
    • 1
  • F. Rouais
    • 1
  • A. Gorodkov
    • 2
  • L. Bordenave
    • 1
  1. 1.INSERM U 443, Université Victor Segalen Boreaux 2Bordeaux CedexFrance
  2. 2.Institut Bakoulev, Scientific Center of Cardiovascular Surgery 8MoscowRussia

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