Skip to main content
SpringerLink
Log in

Bone loss in men

  • Editorials
  • Published:
Calcified Tissue International Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Kanis, JA, Pitt FA (1992) Epidemiology of osteoporosis. Bone 13:S7-S15

    Article  PubMed  Google Scholar 

  2. Cooper G, Campion C, Melton LJ III (1992) Hip fractures in the elderly: a worldwide projection. Osteoporosis Int 2:285–289

    Article  CAS  Google Scholar 

  3. Melton LJ, O'Fallon WM, Riggs BL (1987) Secular trends in the incidence of hip fractures. Calcif Tissue Int 41:57–64

    PubMed  Google Scholar 

  4. Seeman E (1993) Epidemiology and diagnosis of osteoporosis in men. In: Christiansen C, Riis B (eds) Osteoporosis-Proceedings 1993. Aalborg, Denmark, pp 186–189

  5. Cooper C, Atkinson EJ, O'Fallon WM, Melton LJ III (1992) Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minnesota 1985–89. J Bone Miner Res 7:221–227

    PubMed  CAS  Google Scholar 

  6. Agnusdei D, Gerardi D, Camporeale A, Martini G, Gennari C (1994) The European vertebral osteoporosis study in Siena, Italy. Bone 16(1S):118S

    Google Scholar 

  7. Afffram PA, Bauer CGH (1962), Epidemiology of fractures of the forearm. J Bone Joint Surg (A) 44:105–114

    Google Scholar 

  8. Scane AC, Sutcliffe AM, Francis RM (1993) Osteoporosis in men. In: Reid DM (ed) Bailliere's clinical rheumatology-osteoporosis. Bailliere Tindall London, pp 589–601

    Google Scholar 

  9. Russel-Aulet M, Wang J, Thornton J, Colt EWD, Pierson RN (1991) Bone mineral density and mass by total-body dualphoton absorptiometry in normal white and Asian men. J Bone Miner Res 10:1109–1113

    Google Scholar 

  10. Kleerekoper M, Nelson DA, Peterson EL, Flynn MJ, Pawluszka AS, Jacobsen G, Wilson P (1994) Reference data for bone mass, calciotropic hormones, and biochemical markers of bone remodeling in older (55–75) postmenopausal white and black women. J Bone Miner Res 9:1267–1276

    PubMed  CAS  Google Scholar 

  11. Cundy T, Cornish J, Evans M, Gamble G, Stapleton J, Reid JR (1995) Sources of interracial variation in bone mineral density. J Bone Miner Res 3:368–373

    Google Scholar 

  12. Slosman DO, Rizzoli R, Pichard C, Donath A, Bonjour JP (1994) Longitudinal measurements of regional and whole body bone mass in young healthy adults. Osteoporosis Int 4:185–190

    Article  CAS  Google Scholar 

  13. Preece MA, Pan H, Ratcliffe SG (1992) Auxological aspects of male and female puberty. Acta Paediatric (suppl) 383:11–13

    CAS  Google Scholar 

  14. Dequeker J, Aerssens J, Geusens P (1993) Rationale for the use of anabolic steroids in established osteoporosis: pre-clinical experience. In: Christiansen C, Riis B (eds) Osteoporosis-Proceedings 1993. Aalborg, Denmark, pp 306–307

  15. Smith EP, Boyd J, Graeme R, Takahashi H, Cohen R, Specker B, Williams TC, Lubhan DB, Korach KS (1994) Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 16:1056–1061

    Article  Google Scholar 

  16. Johansen JS, Hassager C, Podenphant J, Riis BJ, Hartwell D, Thomsen K, Christiansen C (1989) Bone Miner 6:77–86

    Article  PubMed  CAS  Google Scholar 

  17. Genant HK, Ettinger B, Harris ST, Block JE, Steiger P (1988) Quantitative computed tomography in assessment of osteoporosis. In: Riggs BL, Melton LJ III (eds). Osteoporosis: aetiology, diagnosis and management. Raven Press, New York, pp 221–227

    Google Scholar 

  18. Mosekilde L, Mosekilde L (1990) Sex differences in age-related changes in vertebral body size, density and biochemical competence in normal individuals. Bone 11:67–73

    Article  PubMed  CAS  Google Scholar 

  19. Riggs BL, Wahner HW, Dunn WL, Mazess RB, Offord KP, Melton LJ (1981) Differencial changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest 67:328–335

    Article  PubMed  CAS  Google Scholar 

  20. Mazess RB, Barden HS, Drinka PJ, Bauwens SF, Orwoll E, Bell N (1990) Influence of age and body weight on spine and femur bone mineral density in U.S. white men. J Bone Miner Res 5:645–652

    PubMed  CAS  Google Scholar 

  21. Elliot JR, Gilchrist NL, Wells JE, Turner JG, Ayling E, Gillespie WJ, Sainsbury R, Hornblow A, Donald RA (1990) Effects of age and sex on bone density at the hip and spine in a normal Caucasian New Zealand population. N Z Med J 103:33–36

    Google Scholar 

  22. Nuti R, Martini G, Gennari C (1995) Age-related changes of whole skeleton and body composition in healthy men. Calcif Tissue Int (in press)

  23. Kalender WA, Falsenberg D, Louis O (1989) Reference values for trabecular and cortical vertebral bone density in single and dual-energy computed tomography. Eur J Radiol 9:75–80

    PubMed  CAS  Google Scholar 

  24. Nordin BEC, Aaron J, Speed R, Crilly RG (1981) Bone formation and resorption as the determinants of trabecular bone volume in postmenopausal osteoporosis. Lancet ii:277–279

    Article  Google Scholar 

  25. Aaron JE, Makins NB, Sagreiya K (1987) The microanatomy of trabecular bone loss in normal aging men and women. Clin Orthop 215:260–271

    PubMed  Google Scholar 

  26. Francis RM, Peacock M, Marshall DH, Horsman A, Aaron JE (1989) Spinal osteoporosis in men. Bone Miner 5:347–357

    Article  PubMed  CAS  Google Scholar 

  27. Riggs BL, Melton LJ III (1986) Involutional osteoporosis. N Engl J Med 314:1676–1686

    Article  PubMed  CAS  Google Scholar 

  28. Seeman E (1993) Osteoporosis in men: epidemiology, pathophysiology and treatment possibilities. Am J Med 95(5A):22S-28S

    Article  PubMed  CAS  Google Scholar 

  29. Gray A, Feldman HA, McKinlay JB, Longcope C (1991) Age, disease and changing sex hormone levels in middle-aged men: results of the Massachusetts male aging study. J Clin Endocrinol Metab 73:1016–1025

    PubMed  CAS  Google Scholar 

  30. Gennari C, Agnusdei D, Nardi P, Civitelli R (1990) Estrogen preserves a normal intestinal responsiveness to 1,25-dihydroxy-vitamin D3 in oophorectomized women. J Clin Endocrinol Metab 17:1288–1293

    Google Scholar 

  31. Gennari C (1993) Intestinal calcium transport and aging. In: Christiansen C, Riis B (eds) Osteoporosis-Proceedings 1993, Aalborg, Denmark, pp 16–18

  32. Drinka PJ, Olson J, Bawens S, Voeks SK, Carlson I, Wilson M (1993) Lack of association between free testosterone and bone density separate from age in elderly males. Calcif Tissue Int 52:67–69

    Article  PubMed  CAS  Google Scholar 

  33. Kasperk CH, Wergedal JE, Farley JR, Linkhart TA, Turner RT, Baylink DJ (1989) Androgens directly stimulate proliferation of bone cells in vitro. Endocrinology 124:1576–1578

    PubMed  CAS  Google Scholar 

  34. Colvard DS, Eriksen EF, Keeting PE, Wilson EM, Lubahan DB, Riggs BL, Spelsberg TC (1989) Identification of multiple sex steroid receptors in normal human osteoblast-like cells. Proc Natl Acad Sci USA 86:854–857

    Article  PubMed  CAS  Google Scholar 

  35. Wakley GK, Shutte HD JR, Hannon KS, Turner RT (1991) Androgen treatment prevents bone loss of cancellous bone in the orchidectomized rat. J Bone Miner Res 6:325–330

    PubMed  CAS  Google Scholar 

  36. Seeman E (1995) The dilemma of osteoporosis in men. Am J Med 98(2A):76A-88A

    Article  Google Scholar 

  37. Farley JR, Chesnut CH, Baylink DJ (1981) Improved method for quantitative determination in serum of alkaline phosphatase of skeletal origin. Clin Chem 27:2002–2006

    PubMed  CAS  Google Scholar 

  38. Need AG, Horowitz M, Walker CJ, Chatterton BE, Chapman IC, Nordin BEC (1989) Cross-over study of fat-corrected forearm mineral content during nandrolone decanoate therapy for osteoporosis. Bone 10:3–6

    Article  PubMed  CAS  Google Scholar 

  39. Gennari C, Agnusdei D, Gonnelli S, Nardi P (1989) Effects of nandrolone decanoate therapy on bone mass and calcium metabolism in women with established osteoporosis: a double-blind placebo-controlled study. Maturitas 11:187–197

    Article  PubMed  CAS  Google Scholar 

  40. Fitzsimmons RJ, Wergedal JE, Kasperk C, Baylink DJ (1990) The role of nandrolone decanoate in the treatment of established osteoporosis. In: Christiansen C (ed) Osteoporosis (199). Copenhagen, Denmark, pp 13–18

  41. Canderson D (1992) Osteoporosis in men. BMJ 305:489–490

    Article  Google Scholar 

  42. Rosen CJ, Donahue LR, Hunter SJ (1994) Insulin-like growth factors and bone: the osteoporosis connection. Proc Soc Exp Biol Med 206:83–102

    PubMed  CAS  Google Scholar 

  43. Goldray D, Weisman Y, Jaccard N, Merdler C, Chen J, Matzkin H (1993) Decreased bone density in elderly men treated with the gonadotropin-releasing hormone agonist decapeptyl (d-Trp6-GnRH). J Clin Endocrinol Metab 76:288–290

    Article  PubMed  CAS  Google Scholar 

  44. Vermeulen A (1991) Androgens in the aging male. J Clin Endocrinol Metab 73:221–224

    PubMed  CAS  Google Scholar 

  45. Jackson JA, Kleerekoper M (1990) Osteoporosis in men: diagnosis, pathophysiology, and prevention. Medicine 69:139–152

    Google Scholar 

  46. Riggs BI, Melton LJ III (1986) Involutional osteoporosis. N Engl J Med 314:1676–1686

    Article  PubMed  CAS  Google Scholar 

  47. Endres DB, Morgan CH, Garry PJ, Omdahl JL (1987) Agerelated changes in serum immunoreactive parathyroid hormone and its biological action in healthy men and women. J Clin Endocrinol Metab 65:724–731

    Article  PubMed  CAS  Google Scholar 

  48. Garnero P, Grimaux M, Demiaux B, Predaut C, Seguin P, Delmas P (1992) Measurement of serum osteocalcin with a human-specific two-site immunoradiometric assay. J Bone Miner Res 12:1389–1398

    Google Scholar 

  49. Seibel MJ, Cosman F, Shen V, Gordon S, Dempster DW, Ratcliffe A, Lindsay R (1993) Urinary hydroxypyridinium crosslinks of collagen as markers of bone resorption and estrogen efficacy in postmenopausal osteoporosis. J Clin Endocrinol Metab 7:881–889

    Google Scholar 

  50. Moro L, Pozzi Mucelli R, Gazzarrini C, Modricky C, Marotti F, de Bernard B (1988) Urinary beta-I-galactosyl-0-hydroxylysine (GH) as a marker of collagen turnover of bone. Calcif Tissue Int 42:87–90

    PubMed  CAS  Google Scholar 

  51. Ebeling PR, Peterson J, Riggs BL (1992) Utility of type I procollagen propeptide assays for assessing abnormalities in metabolic bone disease. J Bone Miner Res 11:1243–1250

    Article  Google Scholar 

  52. Seeman E, Melton LJ III, O'Fallon WM, Riggs BL (1983) Risk factors for spinal osteoporosis in men. Am J Med 75:977–982

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Internal Medicine, University of Siena Policlinico Le Scotte, viale Bracci, 53100, Siena, Italy

    C. Gennari & R. Nuti

Authors
  1. C. Gennari
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Nuti
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gennari, C., Nuti, R. Bone loss in men. Calcif Tissue Int 58, 1–3 (1996). https://doi.org/10.1007/BF02509537

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02509537

Search

Navigation