Skip to main content
SpringerLink
Log in

Application of chromatography and coupled chromatography-mass spectrometry for the investigation of pharmacokinetics and metabolism of propofol, clofelin, phencylidine, and tramadol (a review)

  • Structure of Chemical Compounds, Methods of Analysis and Process Control
  • Published:
Pharmaceutical Chemistry Journal Aims and scope

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. B. A. Rudenko, S. A. Savchuk, and E. S. Brodskii,Zh. Anal. Khim.,51(2), 182–201 (1995).

    Google Scholar 

  2. V. M. Mizikov,Diprivan (Appendix to the Journal “Vestn. Intens. Terap.”) [in Russian], Moscow (1995), pp. 1–5.

  3. H. Salomies, P. Lautala, and M. Toppila,Chromatogr., A697 (1–2), 597–601 (1995).

    Article  CAS  Google Scholar 

  4. L. C. Bailey, K. T. Tang, and B. A. Rogozinski,Pharm. Biomed. Anal.,9(6), 501–506 (1991).

    Article  CAS  Google Scholar 

  5. V. Bhattmehta, R. E. Paglia, and D. A. Rosen,Amer. J. Health-System Pharm.,52(2), 192–196 (1995).

    CAS  Google Scholar 

  6. L. C. Bailey, K. T. Tang, and B. A. Rogozinski,Amer. J. Hosp. Pharm.,48(12), 2627–2630 (1991).

    CAS  Google Scholar 

  7. L. W. Hall, E. Lagerweij, A. M. Nolan, and J. W. Sear,Am. J. Vet. Res.,55(1), 116–120 (1994).

    PubMed  CAS  Google Scholar 

  8. J. Guitton, M. Desage, A. Lepape, et al.,J. Chromatogr. Biomed. Appl.,669(2), 358–365 (1995).

    Article  CAS  Google Scholar 

  9. D. Debruyne, J. Tartiere, F. Albessard, et al.,Clin. Drug Invest.,9(1), 8–15 (1995).

    Google Scholar 

  10. H. Y. Yu and J. K. Liau,J. Chromatogr. Biomed. Appl.,615(1), 77–81 (1993).

    Article  CAS  Google Scholar 

  11. S. Z. Fan, H. Y. Yu, Y. L. Chen, and C. C. Liu,Anaesth. Analg.,81(1), 175–178 (1995).

    Article  CAS  Google Scholar 

  12. K. Chan and A. P. C. So,Meth. Find. Exp. Clin. Pharmacol.,12 (2), 135–139 (1990).

    CAS  Google Scholar 

  13. M. H. Shyr, T. H. Tsai, P. P. C. Tan, et al.,Neurosci. Lett.,184(3), 212–215 (1995).

    Article  PubMed  CAS  Google Scholar 

  14. T. B. Vree, A. M. Baars, and P. M. Degrood,J. Chromatogr. Biomed. Appl.,417, 458–464 (1987).

    Article  CAS  Google Scholar 

  15. H. K. Adam, E. J. Douglas, G. F. Plummer, and M. V. Cosgrove,J. Chromatogr.,223, 232–237 (1981).

    PubMed  CAS  Google Scholar 

  16. G. F. Plummer,J. Chromatogr. Biomed. Appl.,421(1), 171–176 (1987).

    Article  CAS  Google Scholar 

  17. M. S. Mazzi,J. Chromatogr.,528, 573 (1990).

    Google Scholar 

  18. P. Altmayer, U. Buch, H. P. Buch, and R. Larsen,J. Chromatogr. Biomed. Appl.,612(2), 326–330 (1993).

    Article  CAS  Google Scholar 

  19. R. H. Pullen, M. A. Curtis, and C. M. Kennedy,J. Chromatogr. Biomed. Appl.,434(1), 271–277 (1988).

    Article  CAS  Google Scholar 

  20. A. L. Dawidowicz and A. Fijalkowska,J. Chromatogr. Sci.,33(7), 377–382 (1995).

    PubMed  CAS  Google Scholar 

  21. B. Kay and G. Rolly,Acta Anaesth. Belg.,28, 303–316 (1977).

    PubMed  CAS  Google Scholar 

  22. I. Pavan, E. Buglione, M. Massiccio, et al.,J. Chromatogr. Sci. 30(5), 164–166 (1992).

    PubMed  CAS  Google Scholar 

  23. R. Beyer and W. C. Seyde,Anaesthetist,41(6), 335–341 (1992).

    CAS  Google Scholar 

  24. D. Debruyne, J. Tartiere, F. Albessard, D. Samba, J. P. Deshayes, and M. Moulin,Clin. Drug Invest.,9(1), 8–15 (1995).

    Google Scholar 

  25. P. P. C. Tan, M. H. Shyr, C. H. Yang, et al.,Neurosci. Lett.,160(2), 205–208 (1993).

    Article  PubMed  CAS  Google Scholar 

  26. M. H. Shyr, C. H. Yang, T. B. J. Kuo, et al.,Neurosci. Lett.,153(2), 161–164 (1993).

    Article  PubMed  CAS  Google Scholar 

  27. I. D. Cockshott, E. J. Douglas, G. F. Plummer, and P. J. Simons,Xenobiotica,22(3), 369–375 (1992).

    Article  PubMed  CAS  Google Scholar 

  28. D. L. Zoran, D. H. Riedesel, and D. C. Dyer,Am. J. Vet. Res.,54(5), 755–760 (1993).

    PubMed  CAS  Google Scholar 

  29. A. Nolan and J. Reid,Br. J. Anaesth.,70(5), 546–551 (1993).

    PubMed  CAS  Google Scholar 

  30. A. M. Nolan, J. Reid, and S. Grant,J. Vet. Pharmacol. Ther.,16(3), 335–342 (1993).

    PubMed  CAS  Google Scholar 

  31. L. W. Hall, E. Lagerweij, A. M. Nolan, and J. W. Sear,Am. J. Vet. Res.,55(1), 116–120 (1994).

    PubMed  CAS  Google Scholar 

  32. R. E. Mandsager, C. R. Clarke, R. V. Shawley, and C. M. Hague,Am. J. Vet. Res.,56(1), 95–99 (1995).

    PubMed  CAS  Google Scholar 

  33. H. Luttropp, R. Thomasson, S. Dahm, et al.,Acta Anaesth. Scand.,38(2), 121 (1994).

    Article  PubMed  CAS  Google Scholar 

  34. P. J. Simons, I. D. Cockshott, E. J. Douglas, et al.,Xenobiotica,21(10), 1243–1256 (1991).

    PubMed  CAS  Google Scholar 

  35. A. A. Raoof, L. J. Vanobbergh, and R. K. Verbeeck,Br. J. Anaesth.,74(1), 46–49 (1995).

    PubMed  CAS  Google Scholar 

  36. R. D. M. Jones, K. Chan, L. J. Andrew, et al.,Meth. Find. Exp. Clinical Pharmacol.,14(1), 41–47 (1992).

    CAS  Google Scholar 

  37. K. Leslie, D. I. Sessler, A. R. Bjorksten, and A. Moayeri,Anaesth. Analg.,80(5), 1007–1014 (1995).

    Article  CAS  Google Scholar 

  38. H. S. Lee, Y. M. Khoo, B. C. Chua, et al.,Therap. Drug Monitor.,17(4), 336–341 (1995).

    Article  CAS  Google Scholar 

  39. M. Hynynen, E. Hammaren, and P. H. Rosenberg,Can. J. Anaesth.,41(7), 583–588 (1994).

    Article  PubMed  CAS  Google Scholar 

  40. O. H. Drummer,J. Forensic Sci.,37(4), 1186–1189 (1992).

    PubMed  CAS  Google Scholar 

  41. T. C. Chao, D. S. T. Lo, P. P. S. Chui and T. H. Koh,Forensic Sci. Int.,66(1), 1–7 (1994).

    Article  PubMed  CAS  Google Scholar 

  42. P. L. Stetson, E. F. Domino and J. R. Sneyd,J. Chromatogr. Biomed. Appl.,620(2), 260–267 (1993).

    Article  CAS  Google Scholar 

  43. P. Veroli, B. Okelly, F. Bertrand, et al.,Br. J. Anaesth.,68(2), 183–186 (1992).

    PubMed  CAS  Google Scholar 

  44. G. Audibert, C. G. Saunier, and P. Dusouich,Drug Metab. Dispos.,21(1), 7–12 (1993).

    PubMed  CAS  Google Scholar 

  45. O. Yu. Kuznetsov and É. É. Ermina, in:Current Problems in Drug Anesthesia [in Russian], St. Petrsburg. Med. Inst., St. Petersburg (1989), pp. 74–78.

    Google Scholar 

  46. K. A. Samoilov and S. L. Zhuchkov, in:Curent Problems in Drug Anesthesia [in Russian], St. Petrsburg. Med. Inst., St. Petersburg (1989), pp. 78–81.

    Google Scholar 

  47. A. A. Zaitsev, in:Current Problems in Drug Anesthesia [in Russian], St. Petrsburg. Med. Inst., St. Petersburg (1989), pp. 62–74.

    Google Scholar 

  48. V. L. Popov, R. V. Babakhanyan, E. S. Bushuev, et al.,Forensic Medical Expertise of Clofelin Poisoning [in Russian], St. Petersburg. Med. Inst., St. Petersburg (1994), p. 74.

    Google Scholar 

  49. P. Hognes,J. Pharm. Pharmacol,28(1), 61–62 (1976).

    Google Scholar 

  50. D. Arndts and T. Arndts,Eur. J. Clin. Pharmacol.,26(1), 79–85 (1984).

    Article  PubMed  CAS  Google Scholar 

  51. E. G. C. Clarce,Isolation and Identification of Drugs, Vol. 1, London (1986), pp. 441–482.

  52. M. L. Levinson and C. E. Johnson,Am. J. Hosp. Pharm.,49(1), 122–125 (1992).

    PubMed  CAS  Google Scholar 

  53. A. J. Nazarali and G. B. Baker,J. Chromatogr.,380, 393–400 (1986).

    PubMed  CAS  Google Scholar 

  54. N. Haring, Z. Salama, G. Reif, and H. Jaeger,Arzneim. -Forsch. Drug. Res.,38-1(3), 404–407 (1988).

    Google Scholar 

  55. Drug Information 87, American Hospital Formulary Service, American Society of Hospital Pharmacists, Inc., Bethesda, MD, USA (1987).

  56. R. F. Arredale, J. T. Stewart, and R. L. Tackett,J. Chromatogr. Biomed. Appl.,432(1), 165–175 (1988).

    Article  Google Scholar 

  57. J. Girault and J. B. Fourtillan,Biomed. Env. Mass Spectrom.,17(6), 443–448 (1988).

    Article  CAS  Google Scholar 

  58. P. O. Edlund,J. Chromatogr.,197, 161 (1980).

    Article  Google Scholar 

  59. L. C. Chu, W. F. Bayne, F. T. Tao, et al.,J. Pharm. Sci.,68, 72 (1979).

    PubMed  CAS  Google Scholar 

  60. S. Murray, K. A. Wadell, and D. S. Davides,Biomed. Mass Spectrom.,500 (1981).

  61. NIDA (National Institute of Drug Abuse) Research Monograph Series 64. Phencyclidine: An Update, Doris H. Clouet (ed.), (1984), p. 64.

  62. V. Dixit and V. M. Dixit,Int. J. Chem. Sect. B. Or. Chem. Med. Chem.,30(2), 164–168 (1991).

    Google Scholar 

  63. V. Verebey and A. Depace,J. Chromatogr. Biomed. Appl.,427(1), 151–156 (1988).

    Article  CAS  Google Scholar 

  64. Information Manual on Designer Drugs (WHO), Vienna (1990), pp. 79–101.

  65. A. K. Cho, M. Hiramatsu, D. A. Schmitz, E. M. Landaw, et al.,Drug Metab. Dispos,21(1), 125–132 (1993).

    PubMed  CAS  Google Scholar 

  66. S. A. Savchuk, B. A. Rudenko, N. A. Davydova, and E. S. Brodskii,Zh. Anal. Khim.,51(12), 1212–1217 (1995).

    Google Scholar 

  67. NIDA Research Monograph Series 32. GC / MS Assays for Abused Drugs in Body Fluids. R. L. Foltz, A. F. Fentiman and R. B. Foltz. (eds.),32, 25–38 (1980).

  68. TIAFT Buuletin., Suppl. H,26(1), 5–34 (1996).

  69. M. B. McClurcan, J. L. Valentine and S. M. Owens,J. Pharm. Exp. Ther.,266(3), 1439–1445 (1993).

    Google Scholar 

  70. C. C. Clark,J. Assoc. Offic. Anal. Chem.,69, 814–820 (1986).

    CAS  Google Scholar 

  71. B. A. Goldberger and E. J. Cone,J. Chromatogr.,674(1–2), 73–86 (1994).

    Article  CAS  Google Scholar 

  72. M. A. ElSohly, T. L. Little, and J. M. Mitchell,J. Anal. Toxicol.,12, 180–182 (1988).

    PubMed  CAS  Google Scholar 

  73. E. J. Holsztynska and E. F. Domino.,J. Anal. Toxicol.,10, 107–115 (1986).

    PubMed  CAS  Google Scholar 

  74. J. R. Woodworth, M. Mayersohn, and S. M. Owens.,J. Anal. Toxicol.,8, 2–6 (1984).

    PubMed  CAS  Google Scholar 

  75. O. Drummer, S. Horomidis, S. Kourtis, et al.,J. Anal. Toxicol.,18, 134–138 (1994).

    PubMed  CAS  Google Scholar 

  76. C. C. Stevenson, D. L. Cibull, G. E. Platoff, et al.,J. Anal. Toxicol.,16, 337–339 (1992).

    PubMed  CAS  Google Scholar 

  77. K. W. Miller and M. R. Michini,Clin. Chem.,34(6), 1273–1273 (1988).

    Google Scholar 

  78. R. D. Budd.,J. Chromatogr.,295, 492–496 (1984).

    Article  PubMed  CAS  Google Scholar 

  79. Varian. Sample Preparation Products, (11), (1996). (see also: http//www.paranoia.com/drugs/war.on.drugs/drug.testing/drugs.of.abuse 1993).

  80. S. S. C. Tai, R. G. Christensen, K. Coakley, et al.,J. Anal. Toxicol.,20, 43–49 (1996).

    PubMed  CAS  Google Scholar 

  81. K. M. Chan, W. S. Matthews, S. Saxena, and E. T. Wong,J. Anal. Toxicol.,17, 299–303 (1993).

    PubMed  CAS  Google Scholar 

  82. M. N. Slawson, D. G. Wilkins, R. L. Foltz, and D. E. Rollins,J. Anal. Toxicol,20(6), 350–354 (1996).

    PubMed  CAS  Google Scholar 

  83. T. Sakamoto, A. Tanaka, and Y. Nakahara,J. Anal. Toxicol.,20, 124–130 (1996).

    PubMed  CAS  Google Scholar 

  84. D. A. Kidwell,Forensic Sci.,38, 272–284 (1993).

    CAS  Google Scholar 

  85. F. Moriya, K. -M. Chan, T. T. Noguchi, and P. Y. K. Wu,J. Anal. Toxicol.,18, 41–45 (1994).

    PubMed  CAS  Google Scholar 

  86. C. M. Moore, D. E. Lewis, and J. B. Leikin,Forensic. Sc.,41(6), 1057–1069 (1996).

    CAS  Google Scholar 

  87. S. K. Eremin, B. N. Izotov, and N. V. Veselovskaya,Analysis of Narcotic Substances [in Russian], Mysl', Moscow (1993), p. 215.

    Google Scholar 

  88. D. A. Armbruster, R. H. Schwarzhoff, B. L. Pierce, and E. C. Hubster,J. Anal. Toxicol.,18, 110–117 (1994).

    PubMed  CAS  Google Scholar 

  89. E. J. Cone, W. D. Darwin, D. Yousefnefad, and W. F. Buchwald,J. Chromatogr.,117, 149–153 (1979).

    Article  Google Scholar 

  90. C. Long and J. Crifasi, D. Maginn,Clin. Chem.,42(11), 1885–1886 (1996).

    PubMed  CAS  Google Scholar 

  91. L. Dan Hoey,GC/MS Application Note. Hewlett-Packard. YH5971a MSD, GC/MS 91-6.

  92. E. J. Cone, W. Buchwald, and D. Yousefnejad,J. Chromatogr.,223, 331–339 (1991).

    Google Scholar 

  93. K. Flick, F. Feldenhaner, P. Jongschaap, and G. Osterlop,Arzneim. -Forsch.,28(1a), 107–113 (1978).

    CAS  Google Scholar 

  94. Tramadol Analgesia: Synergy in Research and Therapy,Drugs,47(Suppl.1), 339–340 (1994).

    Google Scholar 

  95. M. D. Mashkovskii,Drugs [in Russian], Meditsina, Moscow (1994), Vol. 1, p. 194.

    Google Scholar 

  96. E. Frankus, E. Friderichs, S. Kim, and G. Osterloh,Arzneim. -Forsch.,28(1a), 107–113 (1978).

    Google Scholar 

  97. R. B. Raffa, E. Friderichs, W. Reimann, et al.,J. Pharmacol. and Exp. Ther.,267 (Iss1), 331–340 (1993).

    CAS  Google Scholar 

  98. M. Nobilis, J. Pastera, P. Anzenbacher, et al.,J. Chromatogr. Biomed. Appl.,681, 177–183 (1996).

    Article  CAS  Google Scholar 

  99. R. Becker and W. Lintz,J. Chromatogr.,377, 213–220 (1986).

    PubMed  CAS  Google Scholar 

  100. W. Lintz and H. Uragg,J. Chromatogr.,341, 65–79 (1985).

    PubMed  CAS  Google Scholar 

  101. S. A. Savchuk, E. S. Brodsky, B. A. Rudenko, et al.,Int. Congress on Analytical Chemistry, Moscow, Russia, June, 15–21, V1. E-75 (1997).

  102. H. Schuetz,Z. Klinischechem.,17(2), 85–88 (1979).

    CAS  Google Scholar 

  103. B. Elsing and G. Blaschke,J. Chromatogr. Biomed. Appl., 612(Iss2), 223–230 (1993).

    Article  CAS  Google Scholar 

  104. N. V. Veselovskaya, Yu. V. Kislun, S. K. Eremin, et al.,Sud. -Med. Ekspert., 38–42 (1996).

  105. W. D. Paar, P. Frankus, and H. J. Dengler,Clin. Invest.,70(8), 708–710 (1992).

    Article  CAS  Google Scholar 

  106. P. Dayer,Biochem. Biophys. Res. Commun.,125, 374–378 (1984).

    Article  PubMed  CAS  Google Scholar 

  107. W. Lintz, S. Erlacin, E. Frankus, and H. Uragg,Biochem. Biophys. Res. Commun., Bd.31(11), 1932–1943 (1981).

    CAS  Google Scholar 

  108. L. Collart, C. Luthy, C., Favarioconstantin, and P. Dayer,Schweiz. Med. Woch.,123(47), 2241–2243 (1993).

    CAS  Google Scholar 

  109. P. Overback and G. Blaschke,Arch. Pharmacol.,326(9), 682 (1993).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Vernadskii Institute of Geochemistry and Analytical Chemistry, Russian Academy of Sciences, Moscow, Russia

    S. A. Savchuk

  2. Sechenov Medical Academy, Moscow, Russia

    N. V. Veselovskaya & B. N. Izotov

  3. Severtsov Institute of Ecological and Evolutionary Problems, Russian Academy of Sciences, Moscow, Russia

    E. S. Brodskii

  4. Shemyakin Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia

    A. A. Formanovskii

  5. Center for Drug Chemistry, All-Russia Research Institute of Pharmaceutical Chemistry, Moscow, Russia

    V. V. Chistyakov

Authors
  1. S. A. Savchuk
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. V. Veselovskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. S. Brodskii
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. A. Formanovskii
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. V. V. Chistyakov
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. B. N. Izotov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 33, No. 10, pp. 29–52, October, 1999.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Savchuk, S.A., Veselovskaya, N.V., Brodskii, E.S. et al. Application of chromatography and coupled chromatography-mass spectrometry for the investigation of pharmacokinetics and metabolism of propofol, clofelin, phencylidine, and tramadol (a review). Pharm Chem J 33, 545–567 (1999). https://doi.org/10.1007/BF02508379

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02508379

Keywords

Search

Navigation