Skip to main content
Log in

Basic fibroblast growth factor promotes melanin synthesis by melanocytes

  • Short Communication
  • Published:
Archives of Dermatological Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Fitzpatrick TB, Miyamoto M, Ishikawa K (1967) The evolution of concepts of melanin biology. Arch Dermatol 96:305–323

    Article  PubMed  CAS  Google Scholar 

  2. De Luca M, D’Anna F, Bondanza S, Franzi AT, Cancedda R (1988) Human epithelial cells induce human melanocyte growth in vitro but only skin keratinocytes regulate its proper differentiation in absence of dermis. J Cell Biol 107:1919–1926

    Article  PubMed  Google Scholar 

  3. Scott GA, Haake AR (1991) Keratinocytes regulate melanocyte number in human fetal and neonatal skin equivalents. J Invest Dermatol 97:776–781

    Article  PubMed  CAS  Google Scholar 

  4. Halaban R, Ghosh S, Baird A (1987) bFGF is the putative growth factor for human melanocytes. In Vitro 23:47–52

    CAS  Google Scholar 

  5. Halaban R, Tyrrell L, Longley J, Yanden Y, Ruben J (1993) Pigmentation and proliferation of human melanocytes and the effects of melanocyte stimulating hormone and ultra violet light. Ann NY Acad Sci 680:290–300

    PubMed  CAS  Google Scholar 

  6. Eisinger M, Marko O (1982) Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin. Proc Natl Acad Sci USA 79:2018–2022

    Article  PubMed  CAS  Google Scholar 

  7. Aubock J, Kofler D, Sifter M, Fritsch P (1983) Application of the tyrosinase assay to normal melanocytes in culture. Br J Dermatol 109:413–419

    Article  PubMed  CAS  Google Scholar 

  8. Puri N, Mojamdar M, Ramaiah A (1987) In vitro growth characteristics of melanocytes obtained from adult normal and vitiligo subjects. J Invest Dermatol 88:434–438

    Article  PubMed  CAS  Google Scholar 

  9. Puri N, Mojamdar M, Ramaiah A (1989) Growth defects of melanocytes in culture from vitiligo subjects are spontaneously corrected in vivo in repigmenting subjects and can be partially corrected by the addition of fibroblast derived growth factors in vitro. Arch Dermatol Res 281:178–184

    Article  PubMed  CAS  Google Scholar 

  10. Abdel-Malek ZA, Swope VB, Trinkle LS, Norlund JJ (1989) Stimulation of Cloudman melanoma tyrosinase activity occurs predominantly in the G2 phase of the cell cycle. Exp Cell Res 180:198–208

    Article  PubMed  CAS  Google Scholar 

  11. O’Keefe E, Cuatrecasas P (1974) Cholera toxin mimics melanocyte stimulating hormone in inducing differentiation in melanoma cells. Proc Natl Acad Sci USA 71:2500–2504

    Article  PubMed  CAS  Google Scholar 

  12. Abdel-Malek ZA, Swope VB, Pallas J, Krug K, Nordlund JJ (1992) Mitogenic, melanogenic and cAMP responses of cultured neonatal human melanocytes to commonly used mitogens. J Cell Physiol 150:416–425

    Article  PubMed  CAS  Google Scholar 

  13. Stocker KM, Sherman L, Rees S, Ciment G (1991) Basic FGF and TGF-β1 influence commitment to melanogenesis in neural crest-derived cells of avian embryos. Development 111:635–645

    PubMed  CAS  Google Scholar 

  14. Sherman L, Stocker KM, Morrison R, Ciment G (1993) Basic fibroblast growth factor (bFGF) acts intracellularly to cause the differentiation of avian neural crest-derived Schwann cell precursors into melanocytes. Development 118:1313–1326

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Puri, N., van der Weel, M.B., de Wit, F.S. et al. Basic fibroblast growth factor promotes melanin synthesis by melanocytes. Arch Dermatol Res 288, 633–635 (1996). https://doi.org/10.1007/BF02505269

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02505269

Key words

Navigation