Russian Chemical Bulletin

, Volume 46, Issue 11, pp 1909–1911 | Cite as

Synthesis and alkylation ofN-methylmorpholinium 6-amino-3,5-dicyano-4-methylpyridine-2-thiolate

  • V. D. Dyachenko
  • S. G. Krivokolysko
  • V. P. Litvinov
Organic Chemistry

Abstract

The condensation of acetaldehyde with a twofold excess of cyanothioacetamide andN-methylmorpholine givesN-methylmorpholinium 6-amino-3,5-dicyano-4-methylpyridine-2-thiolate. This compound is also formed by recyclization of 2,6-diamino-3,5-dicyano-4-methyl-4H-thiopyran. From this pyridinethiolate, several substituted 2-alkylthiopyridines and 3,6-diamino-5-cyano-4-methyl-2-methoxycarbonylthieno[2,3-b]pyridine were obtained.

Key words

acetaldehyde cyanothioacetamide N-methylmorpholine pyridine thiopyran condensation recyclization 

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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • V. D. Dyachenko
    • 1
  • S. G. Krivokolysko
    • 1
  • V. P. Litvinov
    • 2
  1. 1.T. G. Shevchenko Lugansk State Pedagogical InstituteLuganskUkraine
  2. 2.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation

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