Skip to main content
SpringerLink
Log in

Regulation of cytokine production in the bone marrow during postcytostatic regeneration by SC-1+ and Thy-1+ cells

  • General Pathology and Pathological Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The role of SC-1+ and Thy-1+ cells in the regulation of interleukin-3 production and erythropoietic and colony-stimulating activity of bone marrow cells is studied in cyclophosphamide-treated mice. It is shown that elimination of SC-1+ and Thy-1+ cells has no effect on the production of these cytokines during the early postcytostatic period and upregulates production of some factors stimulating proliferation and colony-formation in the spleen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. E. D. Gol'dberg, A. M. Dygai, and V. P. Shakhov,Tissue Culture in Hematology [in Russian], Tomsk (1992).

  2. A. M. Dygai and V. P. Shakhov,Role of Cell-Cell Interactions in the Regulation of Hemopoiesis [in Russian], Tomsk (1989).

  3. I. V. Miroshnichenko, Prethymic Stage of T Cell development: Properties, Maturation, and Function of T Cell Precursors. Author's Abstract of Ph.D. Thesis, Moscow (1989).

  4. I. V. Miroshnichenko, R. Kh. Aknazarova, and N. I. Sharova,Immunologiya, No. 4, 43–46 (1989).

    Google Scholar 

  5. A. I. Cheredeev and L. V. Koval'chuk, Advances in Sciences and Technology, (Immunology), Moscow (1989).

  6. I. L. Chertkov and O. A. Gurevich,Stem Hemipoietic Cell and Its Microenvironment [in Russian], Moscow (1984).

  7. A. A. Yarilin,Immunologiya, No. 4, 5–14 (1987).

    Google Scholar 

  8. M. Helle, L. Boeije and L. A. Aarden,Eur. J. Immunol.,18, No. 10, 1535–1540 (1988)

    PubMed  CAS  Google Scholar 

  9. A. G. Leary, K. Ikebuchi, Y. Hirai,et al., Blood,71, 1759–1762 (1988).

    PubMed  CAS  Google Scholar 

  10. M. G. Mage, L. L. McHugh, and T. L. Rothstein,J. Immunol. Methods,15, 47 (1977).

    Article  PubMed  CAS  Google Scholar 

  11. M. G. Zsebo, J. Wypych, V. N. Yuschenkoff,et al., Blood,71, 962–965 (1988).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Pharmacology, Tomsk Research Center, Russian Academy of Medical Sciences, USSR

    A. M. Dygai, E. Yu. Sherstoboev & E. D. Gol'dberg

Authors
  1. A. M. Dygai
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. Yu. Sherstoboev
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. D. Gol'dberg
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 4, pp. 374–377, April, 1998

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dygai, A.M., Sherstoboev, E.Y. & Gol'dberg, E.D. Regulation of cytokine production in the bone marrow during postcytostatic regeneration by SC-1+ and Thy-1+ cells. Bull Exp Biol Med 125, 331–333 (1998). https://doi.org/10.1007/BF02499147

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02499147

Key Words

Search

Navigation