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Geographical variation in insertion site number of retrotransposon 412 inDrosophila simulans

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Abstract

The insertion site number of the retrotransposable element 412 was analyzed in natural populations ofDrosophila simulans of worldwide origin by in situ hybridization. We observe a gradient in copy number ranging from as high as 23 in Europe to 1–10 in South Africa, while populations in Madagascar and the Indian Islands, which are the cradle ofD. simulans, have only 3–7 copies. We find very different copy numbers in some local populations of Australia and the Pacific Islands (with around 60 copies in 1 sample and only 5 in another), suggesting spontaneous transposition bursts in local populations. Such bursts occurring now and then in local natural populations followed by fly migration could lead to the progressive invasion of the entire species by the transposable element mobilized, explaining the gradient in 412 copy number between northern and southern hemispheres.

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References

  • Anxolabéhère D, Nouaud D, Periquet G, Tchen P (1985) P-element distribution in Eurasian populations ofDrosophila melanogaster: a genetic and molecular analysis. Proc Natl Acad Sci USA 82:5418–5422

    Article  PubMed  Google Scholar 

  • Aulard S, Lemeunier F, Hoogland C, Chaminade N, Brookfield JF, Biémont C (1995) Chromosomal distribution and population dynamics of the 412 retrotransposon in a natural population ofDrosophila melanogaster. Chromosoma 103:693–699

    PubMed  CAS  Google Scholar 

  • Baba Aïssa F, Solignac M (1984) La plupart des populations deDrosophila simulans ont probablement pour ancêtre une femelle unique dans un passé récent. C R Acad Sci III 299:289–292

    Google Scholar 

  • Baba Aïssa F, Solignac M, Dennebouy N, David J (1988) Mitochondrial DNA variability inDrosophila simulans: quasi absence of polymorphism within each of the three cytoplasmic races. Heredity 61:419–426

    PubMed  Google Scholar 

  • Begun DJ, Aquadro CF (1995) Molecular variation at the vermilion locus in geographically diverse populations ofDrosophila melanogaster andD. simulans. Genetics 140:1019–1032

    PubMed  CAS  Google Scholar 

  • Biémont C (1994) Dynamic equilibrium between insertion and excision of P element in highly inbred lines from an M′ strain ofDrosophila melanogaster. J Mol Evol 39:466–472

    Article  PubMed  Google Scholar 

  • Biémont C (1995) Estimating heterozygosity inDrosophila from transposable element copy numbers. Trends Genet 11:299

    Article  PubMed  Google Scholar 

  • Biémont C, Aouar A, Arnault C (1987) Genome reshuffling of the copia element in aDrosophila melanogaster inbred line. Nature 329:742–744

    Article  PubMed  Google Scholar 

  • Biémont C, Arnault C, Heizmann A, Ronsseray S (1990) Massive changes in genomic locations of P elements in an inbred line ofDrosophila melanogaster. Naturwissenschaften 77:485–488

    Article  PubMed  Google Scholar 

  • Biémont C, Gautier C (1989) Interactions between transposable elements for insertion in theDrosophila melanogaster genome. Heredity 63:125–133

    PubMed  Google Scholar 

  • Biémont C, Lemeunier F, Gautier C, Garcia Guerreiro MP, Aulard S, Pasyukova EG (1994) High rate of movement of one (Mdg3) out of four transposable elements in a natural population ofDrosophila melanogaster. C R Acad Sci III 317:283–286

    Google Scholar 

  • Busseau I, Chaboissier MC, Pélisson A, Bucheton A (1994) I factors inDrosophila melanogaster: transposition under control. Genetica 93:101–116

    Article  PubMed  CAS  Google Scholar 

  • Capy P, Anxolabéhère D, Langin T (1994) The strange phylogenies of transposable elements: are horizontal transfers the only explanation? Trends Genet 10:7–12

    Article  PubMed  CAS  Google Scholar 

  • Capy P, Pla E, David JR (1993) Phenotypic and genetic variability of morphometrical traits in natural populations ofDrosophila melanogaster andD. simulans. I. Geographical variations. Géét Sél Evol 25:517–536

    Google Scholar 

  • Charlesworth B, Charlesworth D (1983) The population dynamics of transposable elements. Genet Res 42:1–27

    Google Scholar 

  • Charlesworth B, Langley CH (1991) Population genetics of transposable elements inDrosophila. In: Selander RK, Clark AG, Whittam TS (eds) Evolution at the molecular level. Sinauer, Sunderland, MA

    Google Scholar 

  • Charlesworth B, Lapid A (1989) A study of 10 transposable elements on X chromosomes from a population ofDrosophila melanogaster. Genet Res 54:113–125

    PubMed  CAS  Google Scholar 

  • Charlesworth B, Lapid A, Canada D (1992) The distribution of transposable elements within and between chromosomes in a population ofDrosophila melanogaster. II. Inferences on the nature of selection against elements. Genet Res 60:115–130

    PubMed  CAS  Google Scholar 

  • Choudhary M, Singh RS (1987) A comprehensive study of variation in natural populations ofDrosophila melanogaster. III. Variations in genetic structure and their causes betweenDrosophila melanogaster and its sibling speciesDrosophila simulans. Genetics 111:697–710

    Google Scholar 

  • Csink AK, McDonald JF (1990) Copia expression is variable among natural populations of Drosophila. Genetics 126:375–385

    PubMed  CAS  Google Scholar 

  • Engels WR (1981) Hybrid dysgenesis inDrosophila and the stochastic loss hypothesis. Cold Spring Harb Symp Quant Biol 45:561–565

    PubMed  Google Scholar 

  • Finnegan DJ, Rubin GM, Young HW, Hogness DC (1978) Repeated gene families in Drosophila. Cold Spring Harb Symp Quant Biol 42:1053–1064

    PubMed  CAS  Google Scholar 

  • Finnegan DJ (1988) The I factor and I-R hybrid dysgenesis inDrosophila melanogaster. In: Berg DE, Howe MM (eds)Mobile DNA. American Society for Microbiology, Washington, DC

    Google Scholar 

  • Gerasimova TI, Mizrokhi LJ, Georgiev GP (1984) Transposition bursts in genetically unstableDrosophila melanogaster. Nature 309:714–716

    Article  Google Scholar 

  • Gvozdev VA (1981) The nature and functions of intercalary heterochromatin inDrosophila melanogaster. In: Molecular basis of genetic processes. Proc XIV Int Congr Genet 3:257–271

    Google Scholar 

  • Hyytia P, Capy P, David JR, Singh RS (1985) Enzymatic and quantitative variation in European and African populations ofDrosophila simulans. Heredity 54:209–217

    PubMed  Google Scholar 

  • Kaplan NL, Darden T, Langley CH (1985) Evolution and extinction of transposable elements in Mendelian populations. Genetics 109:459–480

    PubMed  CAS  Google Scholar 

  • Kidwell MG (1992) Horizontal transfer. Curr Opin Genet Dev 2:868–873

    Article  PubMed  CAS  Google Scholar 

  • Kidwell MG (1983) Evolution of hybrid dysgenesis determinants inDrosophila melanogaster. Proc Natl Acad Sci USA 80:1655–1659

    Article  PubMed  CAS  Google Scholar 

  • Lachaise D, Cariou ML, David JR, Lemeunier F, Tsacas L, Ashburner M (1988) Historical biogeography of theDrosophila melanogaster species subgroup. Evol Biol 22:159–225

    Google Scholar 

  • Leibovitch BA, Glushkova IV, Pasyukova EG, Belyaeva ES, Gvozdev VA (1992) Comparative analysis of retrotransposon localization and mobility in sibling speciesDrosophila simulans andDrosophila melanogaster. Genetika 28:85–97

    Google Scholar 

  • Leigh-Brown AJ, Ross SJ, Alphey LS, Flavell AJ, Gerasimova T (1989) Instability of the ctMR2 strain inDrosophila melanogaster, role of P-element functions and structure of revertants. Mol Gen Genet 218:208–213

    Article  Google Scholar 

  • Montchamp-Moreau C, Ferveur J-F, Jacques M (1991) Geographic distribution of three cytoplasmic incompatibility types inDrosophila simulans. Genetics 129:399–407

    PubMed  CAS  Google Scholar 

  • Montgomery EA, Charlesworth B, Langley CH (1987) A test for the role of natural selection in the stabilization of transposable element copy number in a population ofDrosophila melanogaster. Genet Res 49:31–41

    Article  PubMed  CAS  Google Scholar 

  • Montgomery EA, Langley CH (1983) Transposable elements in Mendelian populations. II. Distribution of copia-like elements in natural populations. Genetics 104:473–483

    PubMed  Google Scholar 

  • Pascual L, Periquet G (1991) Distribution of hobo transposable elements in natural populations ofDrosophila melanogaster. Mol Biol Evol 8:282–296

    PubMed  CAS  Google Scholar 

  • Rubin GM, Kidwell MG, Bingham PM (1982) The molecular basis of P-M hybrid dysgenesis: the nature of induced mutations. Cell 29:987–994

    Article  PubMed  CAS  Google Scholar 

  • Singh RS, Choudhary M, David JR (1987) Contrasting patterns of geographic variation in the cosmopolitan sibling speciesDrosophila melanogaster andDrosophila simulans. Biochem Genet 25:27–40

    Article  PubMed  CAS  Google Scholar 

  • Singh RS (1989) Population genetics and evolution of species related toDrosophila melanogaster. Annu Rev Genet 23:425–453

    Article  PubMed  CAS  Google Scholar 

  • Solignac M, Monnerot M (1986) Race formation, speciation, and introgression withinDrosophila simulans, D. mauritiana, andD. sechellia inferred from mitochondrial DNA analysis. Evolution 40:531–539

    Article  Google Scholar 

  • Spradling AC, Rubin GM (1981) Drosophila genome organisation: conserved and dynamic aspects. Annu Rev Genet 15:219–264

    Article  PubMed  CAS  Google Scholar 

  • Watanabe TK, Kawanishi M (1976) Colonization ofDrosophila simulans in Japan. Proc Jpn Acad 52:191–194

    Google Scholar 

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  1. Laboratoire de Biométrie, Génétique, Biologie des populations, URA C.N.R.S., 2055, Université Lyon 1, 69622, Villeurbanne Cedex, France

    C. Vieira & C. Biémont

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  1. C. Vieira
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  2. C. Biémont
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Vieira, C., Biémont, C. Geographical variation in insertion site number of retrotransposon 412 inDrosophila simulans . J Mol Evol 42, 443–451 (1996). https://doi.org/10.1007/BF02498638

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  • DOI: https://doi.org/10.1007/BF02498638

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