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Bulletin of Experimental Biology and Medicine

, Volume 125, Issue 3, pp 255–258 | Cite as

Synthetic derivative of tuftsin recovers cognitive functions disturbed by antenatal hypoxia

  • T. P. Semenova
  • M. M. Kozlovskaya
  • N. I. Medvinskaya
  • I. I. Kozlovskii
Biophysics and Biochemistry

Abstract

Intraperitoneal injection of synthetic derivate of tuftsin in a dose 300 μg/kg to animals exposed to antenatal hypoxia recovers directed attention and processes of learning and normalizes emotional behavior and the balance between the activities of brain monoaminergic systems. The peptide can be used for compensation of behavioral disorders caused by antenatal hypoxia.

Key words

antenatal hypoxia cognitive process emotions monoamines peptides 

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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • T. P. Semenova
    • 1
    • 2
  • M. M. Kozlovskaya
    • 1
    • 2
  • N. I. Medvinskaya
    • 1
    • 2
  • I. I. Kozlovskii
    • 1
    • 2
  1. 1.Institute of Cell BiophysicsRussian Academy of SciencesPushchino
  2. 2.Institute of PharmacologyRussian Academy of Medical SciencesMoscow

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