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Nitric oxide in paraventricular nuclei of rat hypothalamus under extreme conditions

  • Biophysics and Biochemistry
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The activity of nitroxide synthetase (NOS) was studied histochemically and levels of oxytocin and vasopressin immunocytochemically in rat hypothalamus paraventricular nuclei in on-earth experiments simulating space flight conditions with landing. Colonization of oxytocin and NOS was found in large-cell neurons of paraventricular nuclei. After 15 days under conditions of simulated microgravitation followed by 1-day double gravitation and a short-term (1 day) macrogravitation, activities of NOS and content of neuropeptides increased in large-cell neurons of paraventricular nuclei of experimental animals.

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Authors and Affiliations

  1. Institute of Experimental Endocrinology, Endocrinology Research Center, Russian Academy of Medical Sciences, Moscow

    O. V. Fidelina, O. S. Gorbatyuk & I. G. Akmaev

Authors
  1. O. V. Fidelina
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  2. O. S. Gorbatyuk
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  3. I. G. Akmaev
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 3, pp. 282–284, March, 1998

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Fidelina, O.V., Gorbatyuk, O.S. & Akmaev, I.G. Nitric oxide in paraventricular nuclei of rat hypothalamus under extreme conditions. Bull Exp Biol Med 125, 248–250 (1998). https://doi.org/10.1007/BF02496872

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  • DOI: https://doi.org/10.1007/BF02496872

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