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Induction of prolactin receptors in cholangiocytes of male and female rats after ligation of the common bile duct

  • Microbiology and Immunology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Intense expression of prolactin receptors in cholangiocyte nuclei, nuclear membranes, and cytoplasm was demonstrated by the indirect immunoperoxidase method in intact and gonadectomied male and female rats after ligation of the common bile duct. The intensity of staining increased during cholangiocyte proliferative response to the intervention and, in contrast to hepatocytes, did not depend on animal sex and the presence of the gonads.

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References

  1. O. M. Petrashchuk, A. N. Smirnov, and O. V. Smimova,Byull. Eksp. Biol. Med.,124, No. 9, 351–355 (1997).

    CAS  Google Scholar 

  2. V. B. Rozen, G. D. Mataradze, O. V. Smirnova, and A. N. Smirnov,Sex Differentiation of Liver Functions [in Russian], Moscow (1991).

  3. G. Alpini, R. Lenzi, W. Zhai,et al., Am. J. Physiol.,257, No. 1, Pt. 1, G124-G133 (1989).

    PubMed  CAS  Google Scholar 

  4. A. Buckley, C. Putman, and D. Russel,Adv. Enzyme Regul.,27, 371–391 (1988).

    Article  PubMed  CAS  Google Scholar 

  5. P. Guillaumot and H. Cohen,J. Endocrinol.,141, 271–278 (1994).

    PubMed  CAS  Google Scholar 

  6. Z. Hu, L. Zhuang, and M. Dufau,J. Biol. Chem.,271, No. 17, 10242–10246 (1996).

    PubMed  CAS  Google Scholar 

  7. P. Lobie, J. Garcia-Aragon, and M. Waters,J. Endocrinol.,139, 371–382 (1993).

    Article  PubMed  CAS  Google Scholar 

  8. J. Mainoya,Experientia,37, No. 10, 1083–1084 (1981).

    Article  PubMed  CAS  Google Scholar 

  9. Y. Ni, G. Lukito, G. Marchal,et al., Hepatology,20, No. 6, 1557–1560 (1994).

    PubMed  CAS  Google Scholar 

  10. H. Okamura, K. Zachwieja, S. Raguet, and P. Kelly,Endocrinology,124, No. 5, 2499–2508 (1989).

    Article  PubMed  CAS  Google Scholar 

  11. M. Rodzakis-Adcock and P. Kelly,J. Biol. Chem.,266, No. 25, 16472–16477 (1991).

    Google Scholar 

  12. L. Saperstain, R. Jirtle, M. Farouk,et al., Hepatology,19, No. 2, 412–417 (1994).

    Article  Google Scholar 

  13. P. Slott, M. Liu, and N. Tavolini,Gastroenterology,99, No. 2, 466–477 (1990).

    PubMed  CAS  Google Scholar 

  14. O. V. Smimova, O. M. Petraschuk, and P. A. Kelly,Mol. Cell. Endocrinol.,105, No. 1, 77–81 (1994).

    Google Scholar 

  15. G. Vergani, A. Mayerhofer, and A. Bartke,Tissue Cell,26, No. 3, 457–465 (1994).

    Article  PubMed  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Endocrinology, Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, USSR

    O. V. Smirnova, O. M. Petrashchuk & A. N. Smirnov

Authors
  1. O. V. Smirnova
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  2. O. M. Petrashchuk
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  3. A. N. Smirnov
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 1, pp. 66–70, January, 1998

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Smirnova, O.V., Petrashchuk, O.M. & Smirnov, A.N. Induction of prolactin receptors in cholangiocytes of male and female rats after ligation of the common bile duct. Bull Exp Biol Med 125, 56–60 (1998). https://doi.org/10.1007/BF02496802

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  • DOI: https://doi.org/10.1007/BF02496802

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