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Effect of digoxin on acid hydrolase activity in the myocardium

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Dose-dependent effect of digoxin on cardiac lysosomal enzymes is demonstrated. In doses of 2.5 and 5 mg/kg digoxin suppresses and in a dose of 10 mg/kg increases the activity of myocardial acid hydrolases. By sensitivity to digoxin, the enzymes rank as follows: β-glucosidase>β-galactosidase>acid phosphatase.

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Authors and Affiliations

  1. Russian State Medical University, Moscow

    P. V. Sergeev, L. A. Valeeva & T. V. Ukhina

Authors
  1. P. V. Sergeev
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  2. L. A. Valeeva
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  3. T. V. Ukhina
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 1, pp. 51–55, January, 1998

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Sergeev, P.V., Valeeva, L.A. & Ukhina, T.V. Effect of digoxin on acid hydrolase activity in the myocardium. Bull Exp Biol Med 125, 43–46 (1998). https://doi.org/10.1007/BF02496798

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  • DOI: https://doi.org/10.1007/BF02496798

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