Abstract
C-reactive protein in concentratios of 1–20 mg/ml induces the production of nitrogen oxide by mouse peritoneal macrophages attracted by peptone solution. Protein kinases A and C and RNA and protein production inhibitors abolish this effect, while inhibitors of the lipoxigenase and cycloxigenase pathways of arachidonic acid metabolism attenuate it.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 1, pp. 48–50, January, 1998
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Shebzukhov, Y.V., Vaisburd, M.Y., Artyushkin, K.V. et al. Effect of C-reactive protein on the production of nitric oxide by mouse peritoneal macrophages. Bull Exp Biol Med 125, 40–42 (1998). https://doi.org/10.1007/BF02496797
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DOI: https://doi.org/10.1007/BF02496797