Abstract
Cooling of albino rats in water to brain temperature of 19.6±0.2°C causes almost complete suppression of thermoregulatory muscle tone and shivering because of cold paralysis of the thermoregulatory center. Intravenous injection of 15–20 μM EDTA restores these thermoregulatory reactions at the same temperature.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
N. K. Arokina, A. M. Zharnikov, K. P. Ivanov, and E. A. Lavrova,Dokl. Ross. Akad. Nauk,343, No. 4, 60–62 (1995).
K. P. Ivanov,Byull. Eksp. Biol. Med.,50, No. 11, 19–22 (1960).
K. P. Ivanov,Muscular System and Chemical Thermoregulation [in Russian], Leningrad (1965).
K. P. Ivanov,Principles of Organism's Energetics, Vol. 1.General Energetics, Heat Exchange and Thermoregulation [in Russian], Leningrad (1990).
E. Carafoli,Annu. Rev. Biochem.,56, 395–433 (1987).
Chung-Yuitai, Q. R. Smith, and S. I. Rappoport,Brain Res.,385, No. 2, 227–236 (1986).
R. M. Harnett, J. R. Pruit, and F. R. Siass,Aviat. Space Environ. Med.,54, Pt. 1, 425–434 (1983).
P. W. Hochachka,Science,231, No. 4735 234–241 (1986).
P. W. Hochachka and G. N. Somero, in:Strategies of Biochemical Adaptation. Philadelphia-Lond. -Toronto (1993).
A. D. Weinberg,Ann. Emerg. Med.,22, No. 2, 370–377 (1993).
Author information
Authors and Affiliations
Additional information
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 1, pp. 45–47, January, 1998
Rights and permissions
About this article
Cite this article
Ivanov, K.P., Arokina, N.K. Cold paralysis of the thermoregulatory center and its recovery at paralyzing temperature. Bull Exp Biol Med 125, 37–39 (1998). https://doi.org/10.1007/BF02496796
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02496796